Otsuka Pharmaceutical Factory, Inc.

Mitsui Chemicals, Inc.

Hitoshi Mori

Isamu Tateishi

Yasushi Morimoto

Koichi Igarashi

Ryoji Mori

Nobuaki Sumiyoshi

Yasushi Nagata

Kouichi Igarashi

Rie Ishii

Kenji Konishi

Sadamu Shirokuma

Tetsuya Saito

Toshifumi Mori

A reduced-dissolved-oxygen-content drug solution produced by filling and sealing the drug solution in a drug solution container () formed of a plastic material having an oxygen permeability of not lower than 200 cm/m&#xb7;24 h&#xb7;atm at 25&#xb0; C. at 60% RH within 12 hours after a steam sterilization process or a hot water sterilization process and having a steady-state oxygen permeability of not higher than 100 cm/m&#xb7;24 h&#xb7;atm at 25&#xb0; C. at 60% RH, subjecting the drug solution container to the steam sterilization process or the hot water sterilization process, and storing the drug solution container in an environment having deoxidization means for reducing the dissolved oxygen concentration of the drug solution to not higher than 2 ppm when the oxygen permeability of the plastic material reaches the steady-state level.

Drug solution having reduced dissolved oxygen content, method of producing the same and drug solution containing unit having reduced dissolved oxygen content

A drug solution container package, which can restrain degradation of a drug solution, proliferation of microbes, etc. accompanying the transmission of oxygen in a high degree while maintaining characteristics required of plastic drug solution containers such as heat resistance, impact resistance, pliability, transparency, and resistance against elution of plastic forming material, and to provide a method for manufacturing the drug solution container package. A drug solution is first contained and sealed in a plastic drug solution container having an oxygen gas transmission rate (25&#xb0; C., 60% RH) of not less than 200 cm/m&#xb7;24 h&#xb7;atm within twelve hours after being subject to steam or hot water sterilization, and having an oxygen gas transmission rate (25&#xb0; C., 60% RH) of not more than 100 cm/m&#xb7;24 h&#xb7;atm when the oxygen gas transmission rate is in a steady state, and thereafter the plastic drug solution container is steam sterilized or hot water sterilized and then contained and sealed along with an oxygen scavenger in an outer pouch having an oxygen barrier property.

Drug solution container package and method for manufacturing the same

A pliable plastic film according to the present invention comprises a heat sealable sealing layer, wherein the sealing layer is made of a mixture of a propylene-&#x3b1;-olefin random copolymer having a crystalline melting point Tof 135 to 145&#xb0; C. and a polypropylene (PP) homopolymer having a crystalline melting point Tof higher than 160&#xb0; C.

Pliable plastic film and container using the same

Medical tubes are well balanced in transparency, flexibility, heat resistance, scratch resistance and rubber elasticity. The medical tubes including a propylene polymer composition (A) that contains a polymer with propylene units, at least part of the polymer having an isotactic structure and the total of the propylene units of the polymer being in an amount of 65 to 82 mol % (the total of the structural units of the polymer in the composition is 100 mol %), and that satisfies the following (a1), (a2) and (b1):

Medical tubes

The object of the present invention is to provide a gas barrier film suitable for medical uses, which is excellent in gas and vapor properties and can prevent ingredients of an adhesive and the like from eluting even after heating and sterilizing treatment, and a medical bag using the gas barrier film. A medical gas barrier film of the present invention comprises a multilayer gas barrier filmincluding a deposition oriented polyester layerhaving a deposited layerof an inorganic oxide on one surface, an oriented polyamide layeradhered to the surface of the deposited layerand a polyethylene layeradhered to the surface on the opposite side to an adhered surfaceof the oriented polyamide layer, and a multilayer substrate filmincluding a cyclic olefin polymer layer, an elastomer layersand a heat sealing layer, and the multilayer substrate filmis adhered to an other surfaceon the opposite side of the deposited layer of the deposition oriented polyester layer

Medical gas barrier film and medical bag using the same

Growing community of inventors

Tokushima, Japan

Hitoshi Mori