Nissan Chemical Industries Limited

Other

The University of Tokyo

Yamaguchi University

Linkbio Co., Ltd.

Enthone Incorporated

Hitoshi Furusho

Hiroyoshi Fukuro

Junji Kido

Kenichi Motoyama

Takakazu Nakada

Naoki Otani

Nobuyuki Kakiuchi

Tomoyuki Enomoto

Tatsuo Okauchi

Keitaro Yoshimoto

Yukio Nagasaki

Takuji Yoshimoto

Naoki Nakaie

Tadayuki Isaji

Mikio Kasai

Yuichi Goto

Akira Yanagimoto

Hisayuki Watanabe

Makoto Wakabayashi

Keiko Kimura

Tohru Minami

Yuki Nohara

Mitsunobu Matsumura

Bernhard Wessling

Masayuki Morita

Nobuko Yoshimoto

Yasuaki Mukai

Katsumi Chikama

Koji Wakui

Hisae Miyamoto

Rie Gunji

There is provided a plasma annealing device that can change the crystal structure of a film by processing the film (coating) on a substrate and that has excellent productivity. A method for producing a film includes step (A) irradiating a film on a substrate with atmospheric pressure plasma, wherein the crystal structure of a constituent of the film is changed. The step (A) may include generating plasma under atmospheric pressure by energization at a frequency of 10 hertz to 100 megahertz and a voltage of 60 volts to 1,000,000 volts, and directly irradiating the film on the substrate with the generated plasma. A method for changing a crystal structure of a constituent of a film includes step (A). A plasma generation device used in step (A). An electronic device produced through step (A).

Plasma annealing method and device for the same

The present invention relates to a method for screening a nucleic acid aptamer comprising: (a) contacting a target molecule immobilized on a solid phase support with a nucleic acid aptamer candidate; (b) collecting the nucleic acid aptamer candidate binding with the target molecule by a capillary electrophoresis; and (c) amplifying the nucleic acid aptamer candidate by PCR.

Methods for screening nucleic acid aptamers

The objective of the present invention is to provide a DNA aptamer that can specifically binding to a molecular targeted medicine, a composition comprising the DNA aptamer, and a method for detecting a molecular targeted medicine using the DNA aptamer. A DNA aptamer comprising specifically binding to a molecular targeted medicine, a composition for detecting a molecular targeted medicine comprising the DNA aptamer, a kid for detecting a molecular targeted medicine, and a method for detecting a molecular targeted medicine comprising using the DNA aptamer.

DNA aptamers binding to molecular targeted agents and detection method of molecular targeted medicine using the same

[Problem] To provide a novel nucleic acid aptamer for a vascular endothelial growth factor receptor, said nucleic acid aptamer being useful for the diagnosis and treatment of various diseases associated with VEGFs that can regulate angiogenesis and receptors for the VEGFs, e.g., tumor angiogenesis, diabetic retina and chronic rheumatoid arthritis. [Solution] A nucleic acid aptamer characterized by comprising a nucleotide sequence represented by any one of SEQ ID NOs: 1 to 5, and also characterized by being capable of bonding to a human VEGF receptor specifically. In a preferred embodiment of the nucleic acid aptamer, a primer recognition sequence, a fluorescent label, or a biotin molecule, an avidin molecule, a streptavidin molecule or other specific binding tag peptide may be linked to the 5'- or 3&#x2032;-terminal of the nucleic acid aptamer for the purpose of making it possible to detect the nucleic acid aptamer easily.

Nucleic acid aptamers binding to vascular endothelial growth factor receptors

Described is a doping technique that forms a stable amorphous silicon film and a stable polycrystalline silicon film at a low temperature and simultaneously that imparts conductivity in an atmospheric pressure environment. A method for producing a compound containing a bond between different elements belonging to Group 4 to Group 15 of the periodic table, the method including: applying, at a low frequency and atmospheric pressure, high voltage to an inside of an electric discharge tube obtained by attaching high-voltage electrodes to a metal tube or an insulator tube or between flat plate electrodes while passing an introduction gas, so as to convert molecules present in the electric discharge tube or between the flat plate electrodes into a plasma; and applying the plasma to substances to be irradiated, the substances to be irradiated being two or more elementary substances or compounds.

Method for forming bond between different elements

A metal nanoparticle material for molecular sensing, that includes a metal nanoparticle aggregate including three to ten metal nanoparticles connected to each other through an organic molecule so that adjacent metal nanoparticles are bonded and spaced apart a predetermined distance, the aggregate containing a Raman active molecule within a field applied to the aggregate, wherein the metal nanoparticle material emits enhanced Raman scattering light from the Raman active molecule in an enhanced electric field; a method for producing the metal nanoparticle material for molecular sensing; and a molecular sensing method using the metal nanoparticle material for molecular sensing.

Metal particles for surface-enhanced raman scattering and molecular sensing

A thiophene compound having a phosphate group, for example, one represented by the formula [1]. The compound has high resistance to heat and oxidation and can be improved in solubility or dispersibility in various solvents. (In the formula, Rand Reach independently represents, e.g., hydrogen, halogeno, cyano, or phenyl optionally substituted by W; and Rto Reach independently represents &#x2014;OR, SR, or &#x2014;NR, provided that Rto Reach independently represents hydrogen, Calkyl, or phenyl optionally substituted by W and W represents halogeno, cyano, nitro, hydroxyl, mercapto, amino, formyl, carboxy, Calkyl, etc.)

Thiophene compound having phosphoric ester and process for producing the same

A thiophene compound having sulfonyl groups which is represented by the formula [1]. It has high heat resistance and high unsusceptibility to oxidation and can improve solubility and dispersibility in various solvents. [In the formula, Rand Reach independently represents hydrogen, halogeno, cyano, etc.; and Rand Reach independently represents Calkyl, Chaloalkyl, phenyl optionally substituted by W, thienyl optionally substituted by W, etc. (W represents chlorine, etc.).]

Thiophene compound having sulfonyl group and process for producing the same

An aminoquinoxaline compound represented by the following formula (1), and a polyaminoquinoxaline compound obtained by polymerizing the aminoquinoxaline compound, wherein Rand Rindependently represent a hydrogen atom, a hydroxyl group, a C-Calkyl group, a C-Calkoxy group, or the like, Rand Rindependently represent a hydrogen atom, a halogen atom, a cyano group, a nitro group, an amino group, a C-Calkyl group, a C-Calkoxy group or the like, and Xrepresents &#x2014;NH&#x2014;R&#x2014;NHor &#x2014;NH&#x2014;R.

Aminoquinoxaline compound, polyaminoquinoxaline compound, and use thereof

An electrode for an energy storage device containing a polyaminoquinoxaline compound of the following formula (1a) is provided as having a highly densified energy level and being small in size and light in weight. Rand Rindependently represent a hydrogen atom, a hydroxyl group, a C-Calkyl group, a C-Calkoxy group or the like, Rand Rindependently represent a hydrogen atom, a halogen atom, a cyano group, a nitro group, an amino group, a C-Calkyl group, a C-Calkoxy group or the like, Xrepresents &#x2014;NH&#x2014;R&#x2014;NH&#x2014; or &#x2014;NH&#x2014;R&#x2014; wherein Rand Rindependently represent a C-Calkylene group, &#x2014;C(O)CH&#x2014;, &#x2014;CHC(O)&#x2014; or the like, and n is an integer of 2 or over.

Electrode for energy storage device and process for producing the same

A silica-based coating film on a substrate surface is prepared by forming a reaction mixture comprising a tetraalkoxysilicon compound (A) and/or an alkyl/alkoxy silane compound (B), an alcohol (C), and oxalic acid (D), in such ratios that the amount of alcohol (C) ranges from 0.5 to 100 mols per mol of all alkoxy groups present in the silicon compounds (A) and (B), and the amount of oxalic acid (D) ranges from 0.2 to 2 mols per mol of all alkoxy groups in the silicon compounds (A) and (B), and while maintaining the mixture at a SiOconcentration ranging from 0.5 to 11%, as calculated from silicon atoms in the mixture, by means of the alcohol (C); heating the reaction mixture at a temperature ranging from 50 to 180&#xb0; C. until the total remaining amount of the silicon compounds (A) and (B) in the reaction mixture is not more than 5 mol %, to form a solution of a polysiloxane having a number average molecular weight, calculated on the basis of a polystyrene standard, ranging from 2,000 to 15,000; applying a coating fluid containing the solution of the polysiloxane onto a substrate surface; and thermally curing a coating film obtained by the application, at a temperature ranging from 80 to 600&#xb0; C.

Method of forming thick silica-based film

Disclosed herein are an organic conductive material and a conductive varnish containing it in an amount of 1 to 80 wt %. The organic conductive material comprises an oligoaniline derivative represented by the formula (1) in which quinoimine as an oxidant formed at the time of synthesis is reduced by a reducing agent and a salt is formed with an electron accepting dopant. (where Rto Rindependently denote a hydrogen atom, unsubstituted or substituted monovalent hydrocarbon group, organoxy group, or acyl group; A and B independently denote a divalent group represented by the formula (2) or (3) below; where, Rto Rindependently denote a hydrogen atom, hydroxyl group, unsubstituted or substituted monovalent hydrocarbon group, organoxy group, acyl group, or sulfonic group; and m and n independently denote a positive number equal to or larger than 1 such that m+n&#x2266;20.)

Organic conductive material and conductive varnish

The present invention provides a process for forming a silica-based coating film, characterized by heating a reaction mixture comprising a silicon compound (A) represented by Si (OR)and/or a silicon compound (B) represented by RSi (OR)(wherein n is an integer of from 1 to 3), an alcohol (C) represented by RCHOH and oxalic acid (D) in specific ratios, at a temperature of from 50 to 180&#xb0; C. in the absence of water, to form a solution of a polysiloxane having a number average molecular weight, as calculated as polystyrene, of from 2,000 to 15,000, applying a coating fluid containing such a solution on a substrate surface, and thermally curing a coating film obtained by such coating, at a temperature of from 80 to 600&#xb0; C., and such a coating film having a film thickness of from 0.5 to 5 &#x3bc;m, a coating fluid to be used for such a coating film, and a process for producing such a coating fluid.

An electroluminescent device comprising an anode, a cathode, and at least one electroluminescent organic layer interposed therebetween, wherein a luminescent material in the organic layer emits light upon application of a voltage between the anode and the cathode, is characterized in that a salt of an electron accepting dopant with a polyimide precursor and/or polyimide having oligo-aniline units on side chains is formed as an auxiliary carrier transporting layer between the anode and the organic layer, the polyimide precursor and/or polyimide being obtained from a diamine component containing at least 1 mol % of an oligo-aniline unit-bearing diaminobenzene derivative and a tetracarboxylic dianhydride or derivative thereof.

Growing community of inventors

Funabashi, Japan

Hitoshi Furusho