Piramal Enterprises Limited

Purdue Research Foundation

Hitesh Mistry

Rajiv Sharma

Pravin Gagare

Ashok Kumar Gangopadhyay

Pramod Bhaskar Kumar

Ravindra Dnyandev Jadhav

Narayan Subhash Chakor

Bichismita Sahu

Kishorkumar Shivajirao Kadam

Deepak Singh

Namdev Narayan Borhade

Padi Veeraraghavan Ramachandran

Bidyut Biswas

Sunil Vasantrao Mali

Mahesh Dawange

The present invention relates to a compound of formula I, or an isotopic form, stereoisomer, a tautomer, a pharmaceutically acceptable salt, a solvate, a polymorph, a prodrug, N-oxide or S-oxide thereof; and processes for their preparation. The invention further relates to pharmaceutical compositions containing the compounds and their use in the treatment of diseases or disorders mediated by ROR&#x3b3;.

ROR-gamma modulators and uses thereof

The present invention discloses fused triterpene compounds, represented by the compounds of Formula I (as described herein), processes for their preparation, pharmaceutical compositions comprising the said compounds, their use as retinoid-related orphan receptors gamma (ROR&#x3b3;) modulators and/or interleukin-17 (IL-17) inhibitors and methods for their use in the treatment of a disease or a disorder mediated by ROR&#x3b3; and/or IL-17.

Fused triterpene compounds and uses thereof

A method for synthesizing ammonia borane includes (a) preparing a reaction mixture in one or more solvents, the reaction mixture containing sodium borohydride, at least one ammonium salt, and ammonia; and (b) incubating the reaction mixture at temperatures between about 0&#xb0; C. to about room temperature in an ambient air environment under conditions sufficient to form ammonia borane. Methods for synthesizing ethylenediamine bisborane, and methods for dehydrogenation of ethylenediamine bisborane are also described.

Procedures for the synthesis of ethylenediamine bisborane and ammonia borane

The present invention relates to isoxazole, thiazole and oxidiazole derivatives, processes for their preparation, pharmaceutical compositions containing them and their use as medicaments, in particular to the use of these compounds in the prevention and treatment of diseases or disorders mediated by diacylglycerol acyltransferase (DGAT), particularly DGAT1.

Diacylglycerol acyltransferase inhibitors

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Mumbai, India

Hitesh Mistry