Mitsui Chemicals, Inc.

Hisato Kamekawa

Hiroyuki Katsuta

Toshio Kitashima

Daisuke Ura

Kenichi Satoh

Toshiyuki Kohno

Tomotaka Miyashita

Disclosed is an improved process for producing nitroguanidine derivatives represented by the formula (3), which has an insecticidal activity, or a salt thereof, wherein the substituents are defined herein, in which nitroisourea derivatives represented by the following general formula (1) or a salt thereof wherein the substituents are defined herein, and compounds represented by the following general formula (2) or a salt thereof, wherein the substituents are defined herein, are reacted in the presence of a base in an aqueous solution wherein an inorganic salt is dissolved at not less than 50% of its saturated solubility.

Process for producing nitroguanidine derivatives

Disclosed is an improved process for producing nitroisourea derivatives which is necessary for producing nitroguanidine derivatives having an insecticidal activity. Specifically disclosed is a process for producing nitroisourea derivatives represented by the following general formula (3), which is characterized in that nitroisourea derivatives represented by the following general formula (1) and amines represented by the following general formula (2) or a salt thereof are reacted in the presence of a catalytic amount of a hydrogen carbonate, 

Process for producing nitroisourea derivatives

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Omuta, Japan

Hisato Kamekawa