Hitachi Chemical Company, Ltd.

Tokyo University of Agriculture and Technology

Yamagata University

Hisashige Kanbara

Yoshihito Kikuhara

Takahiro Suzuki

Tomohisa Ohta

Akihiko Dobashi

Yasuyuki Seki

Minoru Tosaka

Tooru Takahashi

Hidekazu Kondou

Yasuhisa Ishida

Hiroyuki Hagiwara

Masafumi Kanetomo

Akio Kotato

Taihei Odagiri

Kyosuke Suzuki

Tsuyoshi Tanaka

Masaru Tanaka

Akishi Nakaso

Tadashi Matsunaga

Kouichi Tsuyama

Takashi Hoshiba

Susumu Naoyuki

Tomoko Yoshino

Toshirou Okamura

Kazuhiro Satou

Ryo Negishi

Chikako Satou

Seita Nakamura

Masami Negishi

Tadayasu Fujieda

Satomi Yagi

Mayo Nikaidou

A cell isolation method includes: a cell trapping step of allowing a test liquid to pass through a cell trapping filter which has a plurality of through-holes in the thickness direction, thereby trapping isolation target cells contained in the test liquid on one surface of the cell trapping filter; a gel embedding step of introducing a stimulus-responsive hydrogel onto the one surface of the cell trapping filter on which the cells have been trapped in the cell trapping step, thereby embedding the cells in the stimulus-responsive hydrogel; a gel hardening step of applying a stimulus to the stimulus-responsive hydrogel in which the cells are embedded, thereby hardening the stimulus-responsive hydrogel; and a detachment step of detaching the stimulus-responsive hydrogel that was hardened in the gel hardening step from the cell trapping filter.

Cell isolation method and cell trapping filter

A metal filter includes a plurality of through holes. An opening shape of each of the plurality of through holes is a rectangle or rounded-rectangle and a length of a short side of the rectangle or a rounded rectangle is 5 to 15 &#x3bc;m. A method for concentrating cancer cells using the metal filter includes separating cancer cells from blood and blood cell constituents by passing blood, red blood cells, white blood cells, and platelets through the plurality of through holes while capturing cancer cells to concentrate the cancer cells.

Metal filter and method for concentrating cancer cells

Provided are a cancer cell-trapping metal filter which has a high opening ratio, a cancer cell-trapping metal filter sheet, a cancer cell-trapping device using the cancer cell-trapping filter, and manufacturing methods therefor. According to a cancer cell-trapping metal filter, openings of connected through-holesthat are formed in a metal sheethave a wave shape, and thus it is possible to extract a CTC from other components by utilizing a hole diameter on a short-side side of the openings, and it is possible to make the connected through-holes be closer to each other due to the wave shape while maintaining a CTC trapping ability. Accordingly, it is possible to further improve the opening ratio in the cancer cell-trapping metal filter

Cancer cell-trapping metal filter, cancer cell-trapping metal filter sheet, cancer cell-trapping device, and manufacturing methods therefor

A cell trapping deviceincludes: a housing, a filter, and a plurality of fastening members. The housingincludes: a lid memberhaving an introduction channelconfigured to introduce a test liquid into an inside; and a storage memberhaving a discharge channelconfigured to discharge the test liquid to an outside. The filter is provided on a channel in the housingand supported between the lid memberand the storage memberby the lid memberand the storage member. The fastening membersconfigured to clamp the lid memberand the storage memberfrom both sides in an intersecting direction that is a direction intersecting with the filter to fasten the lid memberand the storage memberto each other.

Cell trapping device, cell trapping system, and production method for cell trapping device

A polymer comprising a constitutional unit represented by the following formula (1) is useful because when the polymer is applied to a surface of a cancer cell enrichment filter, adhesiveness of cancer cells to the filter surface can be improved so that an enrichment ratio of the cancer cells can be improved. In the formula (1), Ris a hydrogen atom or a methyl group, Ris a methyl group or an ethyl group and m is 1 to 3. 

Agent for improving cancer cell adhesiveness

Filter sheet for a cell collecting cartridge

Cell-collecting cartridge

The invention provides an optical resin composition being transparent, having suitable adhesion and necessary impact absorption for protection of an image display device etc., not affecting constituent materials of a image display panel, and being excellent in reliability, and an optical resin material using the same. Disclosed is an optical resin composition containing (A) a first acrylate derivative that is a compound having one polymerizable unsaturated bond in its molecule, (B) a second acrylate derivative that is a compound having two or more polymerizable unsaturated bonds in its molecule, and (C) an acrylate derivative polymer, and an optical resin material produced by curing reaction of the optical resin composition.

Optical resin composition, optical resin material using the same, optical

An optical resin composition that is transparent, has suitable adhesion and necessary impact absorption for protection of an image display device etc., not affecting constituent materials of a image display panel, and being excellent in reliability, can be used to provide an optical resin material using the same. The optical resin composition contains (A) a first acrylate derivative that is a compound having one polymerizable unsaturated bond in its molecule, (B) a second acrylate derivative that is a compound having two or more polymerizable unsaturated bonds in its molecule, and (C) an acrylate derivative polymer, and an optical resin material produced by curing reaction of the optical resin composition.

Optical resin composition, optical resin material using the same, optical filter for image display device, and image display device

Growing community of inventors

Oyama, Japan

Hisashige Kanbara