Nippon Oil Company

Jx Nippon Oil Energy Corporation

Nippon Oil Corporation

Eneos Corporation

Nippon Mitsubishi Oil Corporation

Jxtg Nippon Oil & Energy Corporation

Hisashi Yoneda

Akira Tsubokura

Takashi Kiyota

Kazuaki Hirasawa

Tetsuhisa Yata

Mitsutoshi Azuma

Hiroshi Satoh

Mikihiro Takaki

Haruyoshi Mizuta

Mikihiro Takai

The present invention provides a method for high yield and stable production of carotenoids through microbial culture. The present invention provides a method for culture of carotenoid-producing bacteria, which comprises culturing carotenoid-producing bacteria in a medium containing cobalt or a cobalt salt at a concentration of 0.005 &#x3bc;mol/L to 20 &#x3bc;mol/L.

Method for producing fermented carotenoid using carotenoid-producing bacteria obtained by using cobalt-containing culturing medium

An object of the present invention is to provide a method for microbioiogically producing astaxanthin of high concentration at low cost while suppressing production of canthaxanthin. Specifically, the present invention relates to a method for producing carotenoids including astaxanthin comprising culturing a bacterium that concurrently produces astaxanthin and canthaxanthin in a medium containing biotin, wherein a ratio of concentration of produced canthaxanthin to concentration of produced astaxanthin in a culture product after the end of culture in the medium is lower than that in a culture product alter the end of culture in a biotin-free medium.

Method for producing astaxanthin by fermentation

An object of the present invention is to provide a method for microbiologically producing astaxanthin of high concentration at low cost while suppressing production of canthaxanthin. Specifically, the present invention relates to a method for producing carotenoids including astaxanthin comprising culturing a bacterium that concurrently produces astaxanthin and canthaxanthin in a medium containing biotin, wherein a ratio of concentration of produced canthaxanthin to concentration of produced astaxanthin in a culture product after the end of culture in the medium is lower than that in a culture product after the end of culture in a biotin-free medium.

The present invention provides a salmon flesh color improving method and a salmon flesh color improving feed which are usable for producing a salmon having a mild reddish orange flesh color close to the flesh color of wild fish, and a salmon and fish flesh thereof produced by such a flesh color improving method. The present invention also provides a method for producing a salmon having a mild reddish orange flesh color, comprising cultivating the salmon with a feed comprising a carotenoid colorant mixed therein, the carotenoid colorant comprising at least astaxanthin, phoenicoxanthin, canthaxanthin and adonixanthin.

Method of improving salmon meat color

A method for microbiologically producing zeaxanthin at high concentration and low cost while suppressing production of gluconic acid is presented. Specifically, a method for producing carotenoids containing zeaxanthin by culturing a bacterium producing carotenoids containing zeaxanthin in a medium containing biotin is provided.

Method for producing zeaxanthin by fermentation

The present invention relates to a process for producing zeaxanthin, &#x3b2;-carotene, or lycopene, comprising inducing mutation in a carotenoid-producing microorganism in which the base sequence of DNA corresponding to 16S ribosomal RNA is substantially homologous to the base sequence described in SEQ ID NO: 1; screening for a mutant strain having a high product proportion of zeaxanthin, &#x3b2;-carotene, or lycopene to the whole production amount of carotenoids to provide a microorganism producing zeaxanthin, &#x3b2;-carotene, or lycopene; culturing the mutant microorganism; and harvesting zeaxanthin, &#x3b2;-carotene, lycopene or a carotenoid mixture containing the same from the resultant culture.

Process for producing carotenoid compound

This invention provides a pigment-containing substance for feed additives consisting of a microorganism culture precipitate which contains a high concentration of carotenoid compounds. This pigment-containing substance for feed additives is resistant to oxygen, light and so on, and can be stably conserved for a long time period.

Pigment- containing materials to be added to feeds

Bacterium belonging to a new genus, and a process for production of carotenoid pigment selected from the group consisting of astaxanthin, adonixanthin, .beta.-carotene, echinenone, canthaxanthin and zeaxanthin, comprising the steps of culturing a bacterium capable of producing at least one of the carotenoid pigments, and recovering an individual carotenoid pigments. The producer bacterium belongs to new genus. According to the present process various carotenoids can be produced in an industrial scale. By the present process (3S, 3'S)-astaxanthin can be produced in an almost 100% purity.

Bacteria for production of carotenoids

Bacteria belonging to new genus process for production of carotenoids

A process for production of canthaxanthin comprising the steps of culturing a microorganism capable of producing canthaxanthin and belonging to the genus Corynebacterium, such as Corynebacterium sp. SQH 348 (FERM BP-4284), and recovering canthaxanthin from the culture.

Process for production of canthaxanthin

A process for the production of an optically active 3-methyladipic acid represented by the formula (I): ##STR1## wherein the symbol * represents an asymmetric carbon atom, comprising the steps of culturing a microorganism belonging to the genus Candida and capable of producing the optically active 3-methyladipic acid in a medium containing squalene, to produce an optically active 3-methyladipic acid; and recovering the optically active 3-methyladipic acid from the cultured product.

Process for production of optically active 3-methyladipic acid from

A process for the production of methylsuccinic acid represented by the formula (I): ##STR1## wherein the symbol * represents an asymmetric carbon atom, comprising the steps of culturing Candida in a medium containing squalene and producing methylsuccinic acid.

Growing community of inventors

Tokyo, Japan

Hisashi Yoneda