Toyama Chemical Co., Ltd.

Hisashi Minami

Hiroshi Sakai

Isamu Saikawa

Takashi Yasuda

Takako Hori

Shohachi Murakami

Hisatsugu Tsuda

Toyoo Maeda

Kenzo Tamai

Yoshiko Yamamoto

Masatoshi Sugita

Joji Nakano

Kenji Takeda

Toru Hiraiwa

Nobuo Terashima

Hiroyo Kawafuchi

Kunikazu Furuhata

Tadakazu Takakura

Makoto Takata

Toyokazu Kobayashi

1,2-benzoisoxazole derivative or its salt and brain-protecting agent

Novel substances having carcinostatic and immunostimulating activity, which are obtained from a culture or its supernatant fluid prepared by culturing bacteria belonging to Fusobacterium genus. Said substances are useful for the treatment of cancerous diseases lower warm-blooded animals. This disclosure concerns such substances and a process for preparing the same and a carcinostatic agent containing the same.

Novel substances having carcinostatic and immunostimulating activity,

Novel TF-2 substances having antitumor and immunostimulating activity, which are obtained from a culture or its supernatant fluid prepared by culturing bacteria belonging to Fusobacterium genus. Said substances are useful for the treatment of cancerous diseases of the mammals including human beings. This disclosure concerns such substances and a process for preparing the same and an antitumor agent containing the same.

Novel substances having antitumor and immunostimulating activity,

This invention relates to a process for producing a TF-500 substance having carcinostatic and immunostimulating activities, which comprises subjecting organisms belonging to the Fusobacterium genus to extraction treatment with a dialkyl sulfoxide and obtaining said TF-500 substance from the resulting extract.

Process for preparing substance having carcinostatic and

Novel TF-2 substances having carcinostatic and immunostimulating activity, which are obtained from a culture or its supernatant fluid prepared by culturing bacteria belonging to Fusobacterium genus. Said substances are useful for the treatment of cancerous diseases of the mammals including human being. This disclosure concerns such substances and a process for preparing the same and a carcinostatic agent containing the same.

Substances having carcinostatic and immunostimulating activity

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Toyama, Japan

Hisashi Minami