Mitsubishi Electric Corporation

Mitsubishi Denki Kabushiki Kaisha

Renesas Technology Corp.

Nec Corporation

Hitachi, Ltd.

Hisashi Harada

Taizo Honda

Yuehu Pu

Masahiro Ikeda

Takaaki Iwata

Toshihiro Otani

Kazushi Hanakawa

Yukiko Yamada

Takahiro Miki

Osamu Takahashi

Tadashi Katayose

Yuichi Yamamoto

Hideo Matsui

Katsuhisa Yoshida

Yusuke Sakamoto

Kengo Sugahara

Hidenobu Sakamoto

Shinichi Hirose

Kazuo Yamamoto

Hiroshi Otani

Hirofumi Tanaka

Nobuyuki Zumoto

Takahisa Nagayama

Hiromitsu Inoue

Shuhei Odawara

Nobuhiko Ina

Yasuyuki Takatani

Toshiaki Koyama

Yue Hu Pu

Akihiko Hoshi

Yuehu Fu

In a particle beam irradiation apparatus that controls a scanning apparatus so that each irradiation position is irradiated with a particle beam a rescan-count number of times by repeating for the rescan-count number of times the irradiation of all irradiation positions in the irradiation target, the irradiation apparatus includes a calculator that receives either one of a rescan count n or a beam intensity J that is a particle beam dose per unit time, to calculate a maximum value of the other satisfying the following conditional expression (P1) for all irradiation positions to present the maximum value to a user.&#x2003;&#x2003;(P1)

Particle beam irradiation apparatus

A particle beam irradiation apparatus radiates a particle beam plural times per one irradiation position. A storage unit stores a dose to be radiated each of the times (divisional target dose). A dose monitor measures the dose of the particle beam radiated to the irradiation position. At the first time of radiation, a controller outputs an interruption signal when the dose measured by the dose monitor reaches the divisional target dose. The dose monitor measures a dose (excessive dose) radiated after the interruption signal is outputted until the particle beam is actually interrupted. Then, it is defined: Corrected Dose value=Divisional Target Dose&#x2212;Excessive Dose Value. Instead, it may be defined: Corrected Dose value=Divisional Target Dose&#x2212;Excessive Dose Estimation Value. At the second time of radiation, the controller outputs an interruption signal when the dose measured by the dose monitor reaches the corrected dose value.

An irradiation apparatus radiates a particle beam after forming the beam for plural layers. A dose monitor measures a dose in real time. A dose evaluation unit evaluates an irradiation dose for each layer on the basis of a value measured by the dose monitor and a dose calibration factor set for each layer. An irradiation control section performs radiation control for each layer on the basis of an evaluation result of the dose evaluation unit. An interpolation value generation unit uses actual-measurement dose-calibration factors obtained by radiating a particle beam to a simulated phantom provided with a calibration dosimeter, to generate an interpolation estimation value of the dose calibration factor. For each layer subject to the interpolation value, and based on an irradiation condition of that layer, the interpolation value generation unit performs weighting on each of the actual-measurement dose-calibration factors.

Particle therapy device and method for setting dose calibration factor

In the particle beam therapy system, a beam transport system includes a beam-path changer for changing a beam path so as to transport a charged particle beam to any one of the plurality of particle beam irradiation apparatuses; and a treatment management device includes a beam-path controller that generates an emitter control signal for controlling an emitter of an accelerator and a beam-path changer control signal for controlling the beam-path changer so that, with respect to the plurality of particle beam irradiation apparatuses in which treatment is performed at the same treatment period of time, the charged particle beam is transported to each one of the plurality of particle beam irradiation apparatuses for each time period allocated thereto.

Particle beam therapy system

A particle beam treatment system includes an accelerator system that accelerates a charged particle beam and a beam transport system that transports a high-energy beam emitted from the accelerator to an irradiation location, wherein the beam transport system is provided with at least one steering electromagnet and at least one beam position monitor corresponding to the at least one steering electromagnet, and wherein the at least one beam position monitor supplies an excitation current for correcting a beam position, which periodically varies, to the at least one steering electromagnet.

Particle beam treatment system and beam position correcting method thereof

In a particle beam therapy system which scans a particle beam and irradiates the particle beam to an irradiation position of an irradiation subject and has a dose monitoring device for measuring a dose of the particle beam and an ionization chamber smaller than the dose monitoring device, the ionization chamber measuring a dose of a particle beam passing through the dose monitoring device, the dose of the particle beam irradiated by the dose monitoring device is measured; the dose of the particle beam passing through the dose monitoring device is measured by the small ionization chamber; and a correction coefficient of the dose measured by the dose monitoring device corresponding to the irradiation position is found based on the dose of the particle beam measured by the small ionization chamber.

Sensitivity correction method for dose monitoring device and particle beam therapy system

A particle beam irradiation apparatus according to the present invention is provided with a vacuum duct that forms a vacuum region through which the charged particle beam passes, a vacuum window through which the charged particle beam is launched from the vacuum region, a scanning electromagnet that scans the charged particle beam; a monitoring apparatus including a position monitor that detects the passing position of a charged particle beam and the beam size thereof, a low-scattering gas filling chamber including the monitoring apparatus, and an irradiation management apparatus that controls irradiation of the charged particle beam; the particle beam irradiation apparatus is characterized in that the low-scattering gas filling chamber is changeably disposed in such a manner that the beam-axis-direction positional relationship between the monitoring apparatus and the vacuum window is a desired one and in that the low-scattering gas filling chamber is filled with a low-scattering gas.

Particle beam irradiation apparatus having adjustable low-scattering filling chamber and particle beam therapy system

The particle beam irradiation apparatus comprises: a position monitor that detects a passing position of a charged particle beam; and an irradiation control apparatus that calculates a distance from a predetermined reference point to the position monitor, calculates a beam irradiation position on an irradiation subject, and controls irradiation of the beam; wherein the irradiation control apparatus includes a position calculation apparatus that calculates the beam irradiation position, based on a beam position detected by the position monitor, a scanning starting point distance information on a distance from a irradiation plane of the irradiation subject to a scanning starting point, of the beam, in a scanning electromagnet, and a position monitor distance information on a distance, from the irradiation plane to the position monitor, that is calculated based on the calculated distance.

Particle beam irradiation apparatus and particle beam therapy system utilizing a beam position monitor to provide feedback adjustments based on the beam position

A control unit is provided with, a retaining section that retains a plurality of operation patterns each being a pattern of operation to be periodically repeated by an accelerator, the operation patterns having respective operation conditions adjusted for different emission times of an particle beam, to cause a deflection electromagnet in the accelerator to have an intended magnetic field intensity even under a presence of a hysteresis; a reading section for a plurality of slices of an irradiation target in a depth direction, which reads an irradiation condition for each of the slices; a selection section that selects the operation pattern suitable for each of the slices, on the basis of the read irradiation condition; and a main control section that controls, for each of the slices, the accelerator on the basis of the selected operation pattern and an irradiation device on the basis of the irradiation condition.

Particle beam therapy device and particle beam therapy device operation method

A particle beam therapy system comprising a treatment table, a treatment table control unit and an irradiation control unit configured to output an instruction for controlling the treatment table control unit, an accelerator and a scanning electromagnet, wherein after the treatment table control unit controls the treatment table so as for a patient isocenter which is reference position of an affected area of a patient to move to a position of an irradiation isocenter which is set at a position which is closer to an irradiation nozzle than an equipment isocenter which is reference of positional relation of the irradiation nozzle and the treatment table, the irradiation control unit outputs an instruction for irradiating the patient with a particle beam.

In order to obtain a particle beam irradiation apparatus that enlarges the dose distribution of beam spots while suppressing a decrease of the maximum available range of a charged particle beam, the particle beam irradiation apparatus includes a particle beam acceleration means; particle beam transport means; scanning apparatus that includes first scanning means and second scanning means, and two-dimensionally scans the beam; and irradiation control means that controls the scanning apparatus so as to irradiate the beam onto a target region including a plurality of small regions. The irradiation control means controls the first scanning means so as to scan the beam over a small region serving as an irradiation subject among the plurality of the small regions, and controls the second scanning means so as to change the small region serving as the irradiation subject to be a different small region among the plurality of the small regions.

Particle beam irradiation apparatus utilized in medical field

A charged particle beam position monitor is provided with a plurality of position monitors and a beam data processing device that performs calculation processing of the state of a charged particle beam, based on a plurality of signals outputted from the position monitors. The beam data processing device includes a plurality of channel data conversion units that perform AD conversion processing of the plurality of signals outputted from the position monitors; a position size processing unit, for each of the position monitors, that calculates the beam position of the beam, based on voltage information obtained through the AD conversion processing; and an integrated control unit that controls the plurality of channel data conversion units in such a way that while the beam is irradiated onto an irradiation subject, AD conversion processing of the signals is performed at different timings for the respective position monitors.

Beam position monitor and particle beam therapy system

A particle beam irradiation apparatus comprises a particle beam shielding member which shields a part of a particle beam which is scanned, a prompt signal detector which detects a prompt signal which is generated when the particle beam which is scanned collides with the particle beam shielding member and a signal comparison device which predicts and obtains a generation pattern of a prompt signal which is generated with a predetermined scanning pattern and stores as a signal time pattern for comparison, wherein the signal comparison device detects an abnormality of scanning of a particle beam or the particle beam shielding member by comparing a detected signal time pattern which is a time pattern of a signal which is detected by the prompt signal detector to a signal time pattern for comparison which is stored.

Particle beam irradiation apparatus and particle beam therapy system

A particle beam therapy system is provided with high irradiation flexibility that can reduce the amount of irradiation onto normal tissue. There are provided (i) a scanning electromagnet that performs scanning and outputting in such a way that a supplied charged particle beam is formed in a three-dimensional irradiation shape based on a treatment plan and (ii) deflection electromagnets that switch the orbits for the charged particle beam in such a way that the charged particle beam with which scanning and outputting are performed by the scanning electromagnet reaches an isocenter through a single beam orbit selected from a plurality of beam orbits established between the isocenter and the scanning electromagnet. The distance between the scanning electromagnet and the isocenter is made long.

Growing community of inventors

Tokyo, Japan

Hisashi Harada