Eisai Company, Limited

Maxell Holdings, Ltd.

Hiroyuki Yoshimura

Shinya Abe

Isao Yamatsu

Koukichi Harada

Kazuo Okano

Mitsuaki Miyamoto

Shuhei Miyazawa

Shigeki Hibi

Mitsuo Nagai

Kouichi Kikuchi

Tetsuya Kawahara

Naoyuki Shimomura

Takayuki Hida

Katsuya Tagami

Takeshi Suzuki

Shigeru Souda

Yoshimasa Machida

Osamu Asano

Kouichi Katayama

Kenzo Muramoto

Richard S Clark

Takashi Yamanaka

Seiko Higashi

Hironori Ikuta

Kenji Hayashi

Kouji Nakamoto

Youji Yamagishi

Kozo Akasaka

Tohru Fujimori

Kenji Tai

Seiichi Kobayashi

Kouji Yamada

Makoto Okita

Hiroshi Obaishi

Satoshi Katayama

Hajime Tsunoda

Naoki Tokuhara

Takashi Mori

Yoshimori Sakuma

Ieharu Hishinuma

Junichi Nagakawa

Makoto Asada

Norimasa Miyamoto

Aichi Ogasawara

Hisashi Shibata

Takashi Sato

Yorihisa Hoshino

Tsutomu Kawata

Kazuo Hirota

Junsaku Nagaoka

Masanori Mizuno

Tsutomu Yoshimura

Hiromasa Suzuki

Yasushi Okamoto

Takashi Inoue

Kenichi Chiba

Naoki Kobayashi

Ryoichi Hashida

Toru Horie

Kenichi Kusube

Yumiko Nagasaka

Koichi Kikuchi

Osamu Igarashi

Hiroshi Shirota

Chikako Kiyose

Shigehiro Yoshitake

Motohiro Soejima

Tatsuya Yoshiuchi

Kazuo Kondo

Koji Yamada

Katsuhiro Moriya

Masashi Yoshimura

Yoshinori Sakuma

Hironobu Nagano

Keizo Sato

Kanryo Terasawa

Akira Takagi

Shigeru Akasofu

Hirsohi Shirota

Richar S Clark

Naoyuki Kimomura

Yuki Kanemori

Camera

Information of plant based on color of a surface of plant is acquired from image data obtained by imaging plant, allowing to acquire information of plant at low cost, compared to chlorophyll meter or spectroscopic analyzer. In crop production like rice plant, fertilization management including fertilizer application management like fertilizer amount determination, or other agricultural works, is supported through a smart phone or the like based on data to be observed, like converted leaf color value is calculated from image data obtained by crop imaging. Camera is connected to smart phone. Converted leaf color value can be obtained from image data obtained by imaging leaf of rice plant by camera. Converted leaf color value is transmitted to management server, for example, amount information of applied fertilizer is required in case where converted leaf color value is less than standard, can be obtained as management information for fertilizer application management.

Plant information acquisition system, plant information acquisition device, plant information acquisition method, crop management system and crop management method

The present invention provides a diuretic, sodium ion-excreting agent, medicament for preventing or treating hypertension, medicament for preventing or treating ischemic cardiac diseases, medicament for preventing or treating congestive cardiac insufficiency or medicament for preventing or treating renal diseases, which comprises &#x3b3;-tocotrienol.

&#x3b3;-Tocotrienol-containing diuretics

The present invention provides a method of preventing or treating a disease caused by oxidation in vivo by administering a pharmacologically effective amount of at least one compound selected from the group consisting of: (1) 2,5,7,8-tetramethyl-2-(&bgr;-carboxyethyl)-6-hydroxychromane; and (2) 2,7, 8-trimethyl-2-(&bgr;-carboxyethyl)-6-hydroxychromane. Further, it provides use of a compound selected from the group consisting of (3) &agr;-tocopherol, (4) &agr;-tocotrienol, (5) &ggr;-tocopherol and (6) &ggr;-tocotrienol for generation in vivo of any of the above compounds (1) and (2) to treat a disease caused by oxidated low density lipoprotein (LDL).

Antioxidant containing vitamin E metabolite

Heterocycle-containing carboxylic acid derivative and drug containing the same

Heterocyclic-ring condensed benzothiazine compound

Mono- or polyenic carboxylic acid derivatives

Carboxylic acid derivatives having fused rings

Described is a heterocycle-containing carboxylic acid derivative represented by the following formula (I):

To provide novel compounds relating to retinoid which can substitute for retinoic acid used for preventing and treating several diseases and having antagonism against retinoid. Heterocyclic compounds represented by the general formula (1-I) or physiologically acceptable salts thereof:

Fused-ring carboxylic acid derivatives

The present invention provides a medicament exhibiting excellent retinoic acid receptor agonism. A Carboxylic acid derivative having a fused ring which is represented by the following formula or a pharmacologically acceptable salt thereof: ##STR1## {wherein the symbol ##STR2## represents a single bond or a double bond; X, Y, Z, P, Q, U, V and W are each a group represented by the formula: --O-- or --S--, or a group represented by the formula: ##STR3## [wherein R.sup.k (k: 1 to 8) is hydrogen, halogeno, optionally substituted lower alkyl or the like, with either of R.sup.7 and R.sup.8 being a group represented by the formula: ##STR4## (wherein A and B are each independently an optionally substituted aromatic hydrocarbon ring or an optionally substituted unsaturated heterocycle; and D is optionally protected carboxyl)]}.

Compounds of the formula and compounds of the formula ##STR1## or their salts have the potent ability to bind to retinoic acid receptors thus useful in treating psoriasis and rheumatoid arthritis.

Growing community of inventors

Ibaraki, Japan

Hiroyuki Yoshimura