Sysmex Corporation

Kagoshima University

Mitsubishi Chemical Corporation

Hiroyuki Kabata

Rena Tsuruoka

Ikuro Maruyama

Kana Kawasaki

Yukiko Miura

Hideki Takahashi

Sanai Tsunokuni

Takanobu Katsuki

Atsushi Iwai

Satomi Kishimoto

Katsunori Itoh

Yuta Yamamoto

Disclosed are devices, programs and methods for determining a type of target peptide contained in a test sample, which relate to comparing first to third information on the target peptide obtained from the test sample with first to third information on a known peptide stored in the storage unit; and determining whether or not the target peptide is the known peptide, wherein the first information is a dissociation rate constant when the target peptide dissociates from a protein, in a solid phase carrier in which the target peptide is immobilized on a support through the protein binding to a peptide, the second information is a maximum value of a layer thickness change amount on the support, and the third information is information indicating that a dissociation mode of a peptide and the protein is either a single dissociation mode or a multiple dissociation mode.

Device, non-transitory computer-readable storage medium, and method for determining type of target peptide

Disclosed is a solid-liquid separation method including: sucking a suspension containing particles, through an opening formed at a leading end of a suction nozzle, into the suction nozzle; allowing at least a part of the particles contained in the sucked suspension, to sediment to be clogged in the suction nozzle; and ejecting a liquid inside the suction nozzle, through the opening of the suction nozzle clogged with the particles.

Solid-liquid separation method, solid-liquid separation apparatus, and kit to be used therefor

The present invention provides a method for detection of a basic peptide by mixing a sample suspected to contain the basic peptide and a reagent containing denatured albumin and detecting turbidness due to a complex of the basic peptide and denatured albumin.

Method for detection of basic peptide and reagent for detection of basic peptide

Disclosed is a method of liberating a peptide, the method comprising a step of bringing a self-aggregate of albumin containing a peptide incorporated therein into contact with a solution that contains a compound represented by Formula (I) or (II) defined in the specification at a concentration of 80 mM to 1000 mM and allowing the peptide to be liberated from the self-aggregate of albumin into the solution.

Method of liberating peptide and method of recovering peptide

Disclosed is a method of recovering a peptide including: mixing a liquid sample containing a complex of peptide and protein in blood with a reagent containing at least one selected from the group consisting of Zn, Ca, Li, Ba, Mg, Mn, and a metal compound that forms any of these metal ions to liberate the peptide from the protein in blood; and recovering the liberated peptide.

Method of recovering peptide and method of detecting peptide

The present invention relates to a molecule capable of binding to adrenocorticotropic hormone (ACTH) with high affinity. The present invention also relates to use of the molecule for detection and/or purification of ACTH.

Molecule capable of binding to adrenocorticotropic hormone, and use thereof

A cell dispersion method, a cell dispersing agent and a cell measurement method, each of which can disperse a cell mass while reducing damage to a cell are provided. Upon dispersing a cell mass, a fluororesin particle is used. A cell mass composed of an aggregated of multiple cells is mixed with a fluororesin particle in a liquid medium, thereby separating the cell mass into individual cells to disperse the cells. In addition, the dispersed cells are measured by flow cytometry, thereby carrying out cell measurement.

Cell dispersion method, cell dispersing agent and cell measurement method

A novel method capable of liberating a peptide from a complex of peptide and albumin and the associated method of recovering the peptide are provided. When a liquid sample containing a complex of peptide and albumin undergoes heat treatment, a self-aggregate of albumin formed in the liquid sample. The peptide is simultaneously liberated from the complex and recovered by removing the self-aggregate from the liquid sample.

Growing community of inventors

Kobe, Japan

Hiroyuki Kabata