Canon Kabushiki Kaisha

Toyo Seikan Kaisha, Ltd.

Toyo Seikan Group Holdings, Ltd.

Olympus Corporation

Hiroyuki Hashimoto

Manabu Komatsu

Yohei Murayama

Kazuhiro Ban

Tadashi Okamoto

Tsuneo Imatani

Masafumi Kyogaku

Hideto Monzen

Shuya Satoh

Takeo Tsukamoto

Takeshi Imamura

Hiroshi Hayashi

Shin Kobayashi

Norihiko Utsunomiya

Hironobu Mizuno

Koki Nukanobu

Katsuaki Kuge

Hiromitsu Takase

Kumi Nakamura

Masayuki Sasaki

Hotaka Fukabori

Satoru Nemoto

Takuya Fujikawa

Shoichiro Takano

Yoshinori Tomida

Kimihiro Yoshimura

Yoshitsugu Maruhashi

Toshiaki Aiba

Kota Iwasaki

Mitsuaki Hasegawa

Miki Ogawa

Kiyoshi Kawaguchi

Yoichi Otsuka

Takeshi Iwashita

Nobuyuki Takakusaki

Koichi Tanji

Makoto Etoh

Satoru Hatakeyama

Yoshihiko Kimura

Naofumi Aoki

Kyohei Kurihara

Jun Yonesato

Ken Itou

Jumpei Naito

Tomoaki Kaneko

Hiroyuki Kondou

Koji Makara

Satoru Nemeto

A medical manipulator system including: a placement table on which a patient is placed; at least one manipulator configured to support a treatment tool which is configured to treat the patient, the manipulator configured to adjust a position and an orientation of the treatment tool; a base portion configured to support the manipulator; a sensor configured to detect objects which are present in a predetermined area including the manipulator and the placement table; and a controller including at least one processor, wherein the processor is configured to: calculate degrees of proximity between the objects detected by the sensor and the manipulator, and generate, in case that the calculated degrees of proximity exceed a predetermined threshold, a control signal for preventing interference between the objects and the manipulator.

Medical manipulator system and operating method thereof

A laser scanning microscope apparatus includes an irradiation unit including an objective lens, a photodetector unit, an XY-scanning unit, and a Z-scanning unit. The irradiation unit focuses a laser beam with the objective lens to a specimen. The photodetector unit detects light generated from a position irradiated with the laser beam focused. The XY-scanning unit scans the laser beam in an X-direction perpendicular to an optical axis of the objective lens and in a Y-direction perpendicular to the optical axis and the X-direction. The Z-scanning unit scans the laser beam in a Z-direction parallel to the optical axis. When acquiring XY-two-dimensional image data by detecting the light while scanning the irradiated position in the X-direction and the Y-direction, the apparatus detects the light while scanning the irradiated position also in the Z-direction.

Laser scanning microscope apparatus

A charged particle image measuring device includes a sample stage, a charged particle lens opposite the sample stage, a two-dimensional detector, a first diaphragm disposed between the sample stage and a position of a crossover that is formed by the charged particle lens and that is closest to a sample, and a second diaphragm disposed between the first diaphragm and the two-dimensional detector.

Charged particle image measuring device and imaging mass spectrometry apparatus

When compression molding is performed continuously, lumps of molten synthetic resin (drops), which are supplied by extrusion, are continuously, accurately, and rapidly inserted into plurality of compression molding dies which are rotatingly movable. A method and device for continuously supplying drops into female moldings which are rotatingly movable for manufacturing moldings, wherein synthetic resin in molten condition extruded from an extrusion opening is cut by a cutter attached to a holding mechanism to form the molten resin into drops in a determined quantity, the drops are held and conveyed by the holding mechanism, and the drops are forcibly inserted and supplied into the concaves of the female moldings. At that time the holding mechanism on the rotary-and movable type drop supply is made to approach the rotating molding die and the rotation path of the holding mechanism is made to overlap with that of the molding die within a determined area to make the movement of the holding mechanisms follow that of the molding die.

Method and device for forcibly inserting drop into compression molding machine, and molding die follow-up type method and device for supplying drop

The problem to be solved by the present invention is to provide a method for treating a polypeptide including a cysteine residue for enhancing the sensitivity of detection thereof in mass spectrometry using charged particles. A mass spectrometry method for a polypeptide including a cysteine residue is provided which includes treating the polypeptide including a cysteine residue with a cyanation agent, treating the cyanated polypeptide with a base, and then desorption ionizing the base-treated polypeptides using charged particles for mass spectrometry.

Mass spectrometry method for a polypeptide including a cysteine residue

A method and device for continuously supplying molten synthetic resin drops into female moldings which are rotatingly movable for manufacturing moldings, wherein synthetic resin in molten condition extruded from an extrusion opening is cut by a cutter attached to a holding mechanism to form the molten resin into drops in a determined quantity, the drops are held and conveyed by the holding mechanism, and the drops are forcibly inserted and supplied into the concaves of the female moldings. At that time the holding mechanism on the rotary- and movable type drop supply is made to approach the rotating molding die and the rotation path of the holding mechanism is made to overlap with that of the molding die within a determined area to make the movement of the holding mechanisms follow that of the molding die.

Device for forcibly inserting drop into compression molding machine, and molding die follow-up type device for supplying drop

Provided is a sample analysis method of irradiating a sample with a primary ion beam to analyze a secondary ion emitted from the sample by mass spectrometry, the sample analysis method including the steps of cooling a sample placed in a chamber; forming an ice layer on a surface of the cooled sample by discharging one of water and an aqueous solution to the chamber; and irradiating the surface of the sample with the primary ion beam with the ice layer being formed thereon, wherein an amount of the water forming the ice layer is 0.1 ng/mmor more and 20 ng/mmor less.

Method of analyzing sample using secondary ion emitted from sample and analyzer for performing analysis method

A test apparatus includes a biopsy needle for sampling a biopsy specimen. The biopsy needle includes a specimen holder that holds the sampled biopsy specimen, and an optical window disposed in the specimen holder and configured to allow optical detection. A biopsy specimen held by the specimen holder of the test apparatus is measured by using a third-order nonlinear Raman microscope.

Test apparatus and method of observing biopsy specimen sampled by using test apparatus

A method is provided by which a reagent is provided to a living sample, including contacting a thin-film containing a porous body with a living sample containing cells or tissues, and discharging a solution containing at least one or more reagents to a non-contact side of the thin-film by ink-jet to provide the solution to the specific area of the living sample through pores on the thin-film, wherein the smaller diameter of the pores on the porous body relative to the diameter of cells in the living sample enables the reagent to be provided to each individual cell separately. According to this method, the reagent and the reaction product can be fixed while maintaining positioning information of the target substance in the living sample, as a pretreatment for analyzing with high positioning accuracy the target substance in each individual cell in the living sample.

Method for treating living samples and analyzing the same

A pre-treatment method for analyzing a specified portion in a specimen composed of a biological tissue includes the steps of preparing a specimen to be analyzed, determining a specified portion in the specimen; and applying an analysis inhibitor to a portion except the specified portion of the specimen using a droplet spray method.

Method for pre-treating specimen and method for analyzing specimen

A biological tissue processing substrate for fixing proteins in a biological tissue or degradation products of the proteins, the substrate comprising: a porous body that forms a contact surface with the biological tissue, the porous body holding in pores an enzyme for obtaining the proteins or the degradation products of the proteins from the biological tissue, wherein the proteins or the degradation products obtained by the action of the enzyme are brought into contact with a member consisting of a metal.

Biological tissue processing substrate for fixing proteins or protein degradation products in tissue for analysis

[Problem] To realize a predetermined 'aseptic level of the containers' without introducing a container sterilizing machine and to reduce the burden for adjusting the temperature of the preform. [Means for Solution] A metal mold for molding, wherein a space width (t) of at least the body portion in the space width for forming a thickness of from the body portion to the bottom portion of the preform is set to lie in a range of 1.18 to 2.11 times as great as a space width (t) for forming a thickness of an upper end portion of the mouth portion of the preform. At the time of the compression molding, the preform is taken out in the state of a high temperature from a compression-molding machineand is fed to a bottle-producing unit C while maintaining the state of a high temperature. Further, the inner surfaces of a clean box I in which the units are placed and the outer surfaces of the units are sterilized, and the interior of the clean box I maintains a positive-pressure state with the filtered clean air. The bottle-producing unit C and a filling/sealing unit D are neighboring and directly coupled to each other in the same clean box, and are partitioned by a WBZ

System for aseptically filling a container with a beverage or food

A more effective noise reduction method is provided. In the method, when mass spectrum information having a spatial distribution is processed, the whole data is taken as three-dimensional data (positional information is stored in an xy plane, and spectral information is stored along a z-axis direction), and three-dimensional wavelet noise reduction is performed by applying preferable basis functions to a spectral direction and a peak distribution direction (in-plane direction).

Method and apparatus for reducing noise in mass signal

The invention also provides for an apparatus for feeding molten resin, wherein the apparatus includes holding units each having a respective holding portion that is opened and closed to hold a molten resin that is discharged from an extrusion port of a die head of an extruder and is cut by a cutter while moving on a track, in which, after the respective holding portion transfers the molten resin from the extrusion port to a female mold, a side of the respective holding portion is opened and the molten resin is fed down to the female mold in a compression-molding machine, wherein a plurality of longitudinal grooves extending up and down are formed in an inner circumferential surface of the respective holding portion that holds the molten resin.

Apparatus for feeding molten resin

Target molecules in a sample can be detected at an improved sensitivity by means of a mass spectrometer. A sample with or without a matrix is placed on a substrate and irradiated with a converged and pulsed primary beam selected from an ion beam, a neutral particle beam or a laser beam. Secondary ions and neutral molecules are emitted along with protons from the irradiated point of the sample as an electric field is applied between the substrate and an extraction electrode disposed above the substrate. A proton-control electrode is arranged in axial symmetry with the trajectory of the primary beam. A voltage is applied thereto so that the generated electric field decelerates the flying protons to raise their adhering efficiency to the flying neutral molecules.

Information acquiring apparatus and information acquiring method for acquiring mass-related information

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Yokohama, Japan

Hiroyuki Hashimoto