Osaka University

Hiroyuki Fujita

Iwao Yoshida

Sadao Manabe

Konosuke Fukai

Mitsuo Takagi

Juichiro Osame

Akihisa Takamizawa

Keisuke Takaku

Takeo Konobe

Masahiko Kato

There is disclosed an antigen comprising an amino acid sequence of the suce antigen of a hepatitis B virus. The present antigen can be produced easily and safely at low cost by means of recombinant DNA technique. The present antigen can be used as an effective vaccine and diagnostic for hepatitis B.

Process for expressing the hepatitis B virus antigen using a

There is disclosed a DNA which codes for an antigen comprising at least part of an amino acid sequence of the antigen of a flavivirus, which part contains at least one epitope of the flavivirus antigen. The present DNA can be used for producing the antigen easily and safely at low cost by means of recombinant DNA technique. The antigen produced using the present DNA can be used as an effective vaccine and diagnostic for Japanese encephalitis.

A DNA coding for a Flavivirus antigen

There is disclosed an antigen comprising at least part of an amino acid sence of the antigen of a flavivirus, which part contains at least one of epitopes of the flavivirus antigen. The present antigen can be produced easily and safely at low cost by means of recombinant DNA technique. The present antigen can be used as an effective vaccine and diagnostic for Japanese encephalitis.

Flavivirus antigen

Growing community of inventors

Mitoyo, Japan

Hiroyuki Fujita