Chugai Seiyaku Kabushiki Kaisha

Hiroyuki Eda

Kazuo Hattori

Satoshi Niizuma

Takehiro Okada

Miyuki Yoshida

Kenji Tatsuno

The present invention provides: a compound represented by the following formula (I): [wherein Yand Yrepresent a hydrogen atom or a halogen atom; either one of Yand Yrepresents &#x2014;NRR, and the other represents a hydrogen atom or a halogen atom; X represents an aryl group or a heteroaryl group that may be substituted; Rrepresents a hydrogen atom, or a Calkyl group that may be substituted; and Rrepresents a Calkyl group that is substituted with one or more substituents, &#x2014;COOR, &#x2014;COR, &#x2014;COSR, &#x2014;CONRR, &#x2014;NRR, or &#x2014;C&#x2550;NRR; or Rand R, together with a nitrogen atom to which they are bonded, may form a 4- to 10-membered hetero ring containing at least one nitrogen atom (wherein the hetero ring may be substituted with one or more substituents selected from Group C)], a prodrug thereof, or a pharmaceutically acceptable salt thereof; and a pharmaceutical, a pharmaceutical composition, or the like, which comprises the compound.

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Kanagawa, Japan

Hiroyuki Eda