Director-general of Agency of Industrial Science and Technology

Agency of Industrial Science and Technology

Japan As Represented by Director General of Agency of Industrial Science

Hiroyasu Ishida

Ikuo Matsui

Kazuhiko Ishikawa

Yoshitsugu Kosugi

Akira Sekiya

Masanori Tamura

Katsuhiko Higuchi

Yasutaka Tahara

The invention relates to a thermophilic enzyme having &#x3b2;-glycosidase activity which comprises the amino acid sequence of SEQ ID NO: 2 in which one or a plurality of amino acid residues may be deleted, replaced or added.

Methods for making and using a thermophilic enzyme as a &#x3b2;-glycosidase

A thermostable phosphatidylethanolamine N-methyltransferase and a process for producing the enzyme are provided. A host cell is transformed with an expression vector containing DNA encoding a thermostable enzyme derived from hyper-thermophilic archaea such as Pyrococcus, the enzyme having phosphatidylethanolamine N-methyltransferase activity and an optimum temperature of 90&deg; C. or higher, and the transformed host cell is cultured.

Thermostable enzyme having phosphatidylethanolamine N-methyltransferase activity

An acyl peptide hydrolase having an optimum temperature range of 90-95.degree. C. and a gene encoding the same are disclosed. With the above enzyme, it becomes possible to conduct amino terminal analysis of acylated proteins and peptides at high temperatures.

Thermostable acyl peptide hydrolase and gene encoding the same

A novel fluorine-containing polymeric compound represented by the general formula

Growing community of inventors

Ibaraki, Japan

Hiroyasu Ishida