The Chemo-Sero-Therapeutic Research Institute

Km Biologics Co., Ltd.

Jectas Innovators Company Limited

Hirotaka Uefuji

Takeshi Arakawa

Takeshi Miyata

Tetsuya Harakuni

Ryuichi Sakamoto

Kenji Yokogawa

Kenichi Yamazaki

Kiyohiko Andoh

Kiyotaka Suenaga

Takashi Waki

Yoko Honda

Tomomitsu Sewaki

The present invention is intended to provide an egg drop syndrome (EDS) vaccine that is capable of effectively preventing EDS and can be stably supplied. The EDS vaccine provided to this end contains as an active ingredient fused protein in which a polypeptide having a coiled-coil forming unit is bound to the knob region in the fiber protein of EDS virus (EDSV).

Prophylactic vaccine against egg drop syndrome (EDS)

A purpose is to provide a vaccine which can prevent porcine edema disease in farms where porcine edema disease is anticipated. Meeting this purpose is a vaccine that is a fusion protein in which Stx2eB and a polypeptide having a coiled-coil forming unit are joined or a multimer of the fusion protein, and by immunizing pigs with this vaccine, it is possible to induce potent neutralizing antibodies and to defend against the onset of porcine edema disease.

Vaccine for preventing porcine edema disease

Growing community of inventors

Okinawa, Japan

Hirotaka Uefuji