Fuji Yakuhin Co., Ltd

Hiroshige Kato

Koji Matsumoto

Yoshinobu Aoyagi

Naoki Ashizawa

Seiichi Kobashi

Koichi Ishida

Ryuko Tokuyama

It is intended to provide a novel bisphosphonic acid compound or a salt thereof which shows a remarkable inhibitory effect on ectopic calcification, and a pharmaceutical composition comprising the same. The present invention provides a bisphosphonic acid compound represented by the following formula (1) or a pharmaceutically acceptable salt thereof: whereinrepresents a single bond or a double bond; A represents a saturated cyclic hydrocarbon or a saturated heterocyclic ring comprising a sulfur atom or an oxygen atom; and Rand Reach independently represent an alkyl group, an alkenyl group, an alkynyl group, an alkoxy group, an aryloxy group, a haloalkoxy group, a haloalkyl group, a halogen atom or a hydrogen atom.

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Saitama, Japan

Hiroshige Kato