Zeria-shinyaku Kogyo Kabushiki Kaisha

Nippon Kayaku Co., Ltd

Hiroshi Sato

Shripad S Bhagwat

Paul E Erdman

Hajime Hiratani

Moorthy S S Palanki

Yoshikazu Yuki

Koji Sasaki

Mary Doubleday

Masao Iijima

Kaname Takagi

Hajime Goto

Hiroshi Okano

Yosuke Miyamoto

Neuroprotective agents and methods related thereto

A process for sugar-coating a solid preparation such as tablet, pill, granule or grain with a sugar-coating liquid comprising pullulan and/or a water-soluble derivative thereof dissolved in an aqueous solution of sucrose. The solid preparation sugar-coated by the above-mentioned process exhibits an enhanced impact strength and shelf life.

Process for sugar-coating solid preparation

An anti-inflammatory agent comprising as an active component an inhibitor specifically inhibiting a thiol protease, which is obtained from human urine by extraction and purification. This agent has an action of inhibiting a disease caused by a thiol protease. This anti-inflammatory agent is prepared by a process in which a thiol protease inhibitor is extracted and purified from human urine by adopting in combination at least two treatments selected from a treatment with a molecular filter, a treatment with an ion exchanger, a treatment with an adsorber and an affinity chromatographic treatment.

Process of treating inflammation with human urinary thiol protease

Growing community of inventors

Omiya, Japan

Hiroshi Sato