Hitachi, Ltd.

Other

Hitachi Instrument Engineering Co., Ltd.

Hiroshi Ohki

Ryo Miyake

Isao Yamazaki

Hideyuki Horiuchi

Toshio Kaneko

Shinichi Sakuraba

Hideo Enoki

Ryohei Yabe

Masataka Kawauchi

Ichiro Nakamura

Kazuo Sakai

Masaetsu Matsumoto

Hideki Tanaka

Kazuo Sato

Hisanobu Kanamaru

Yoshio Okamoto

Tohru Ishikawa

Keiji Kataoka

Yoshiyuki Tanabe

Takao Terayama

Kazuo Honma

Yuji Kikuchi

Koji Nakagawa

Tokuo Kosuge

Mizuho Yokoyama

Isao Shindo

Hideaki Kamohara

Satoshi Suzuki

Yasuhiro Nemoto

Kiyoshi Amou

Kihachiro Tanaka

Susumu Kai

Masao Okayama

Fujiya Takahata

Masaharu Ishii

Shigeo Mutou

Nobuyuki Tatara

Hitoshi Maeda

Kaori Yasuda

In order to investigate particles in a fluid, a flow cell causes the fluid to flow past a sensor which receives light from a continuous light emission system. When the sensor detects a change in light, a particle detector is triggered, which in turn triggers a pulse generator and hence an intermittent light emission system. Light then illuminates the flow cell to allow a CCD camera to photograph the particle. The photographs taken by the CCD camera are analyzed by an image processor. In order to obtain an accurate particle concentration measurement, it is necessary to modify the initial concentration measurement derived from the analysis of particle images by the image processor by a compensation coefficient. This operation is carried out by a concentration compensator. The result may then be displayed. Additional analysis may be carried out by changing the magnification of the CCD camera, or by selecting for analysis only those particles of a selected size or type.

Apparatus for investigating particles in a fluid, and a method of

A flow cell apparatus, useful in an apparatus for measuring particles suspended in a liquid, comprises a sample liquid, supply device, a sheath liquid supply device, a flow cell which has a flow passage passing through a transparent measuring portion, and a nozzle for causing the sample liquid, from the supply device to flow in the flow passage of the flow cell. The nozzle has at least one discharge port which is disposed in the flow passage in a spaced relation from the inner wall of the flow cell flow passage. The sheath liquid supply device causes the sheath liquid to flow around the nozzle discharge port and surround the sample liquid flow to form a sheath flow. The flow passage of the flow cell and the nozzle are so formed as to ensure a sample liquid flow of a fixed width through the measuring portion. A stable sample flow having a fixed width can be formed in the measuring portion even when the flow is at a high velocity, and particles in the sample liquid can efficiently be photographed with high accuracy.

Flow cell apparatus

An analytic test sheet feeder comprises a cylindrical container 11 having an elongated through hole 15 formed in a side wall thereof for receiving a test sheet, a container support 18 which comprises an upper portion having a semi-cylindrical concave surface and a hole 20 formed in a central portion of the concave surface to permit a test sheet descending from the through hole of the container 11 to be taken out therethrough 20, and a test sheet delivering stage 31 which receives and delivers the test sheet descending from the through hole 15.

Analytic test sheet feeder

A system for analyzing the operating conditions of electrical apparatus in order for the aged to check the change and abnormal state of life and for the external institute to check the safety of the houses or homes and so on. The data of standard power spectra of particular consumption current for each apparatus are stored in the memory of the system. The electrical signal detected from the wiring conductor is converted into a digital signal by the preprocessor and undergoes fast Fourier transform at the processor so as to be converted into an extracted power spectrum. If the extracted power spectrum includes a particular one of the standard power spectra as a result of comparing this spectrum with the standard power spectra, the operating conditions of that apparatus are stored in the memory with lapse of time. Thus, the life condition/rhythm of the private person can be checked by himself from the operating conditions of apparatus, and also transmitted as life information through the communication network to the outside institutes.

Analyzing system for operating condition of electrical apparatus

An electromagnetic fuel injection valve comprises a valve body, a valve seat which cooperates with the valve body, a fuel injection port disposed downstream of the valve seat, and a dividing device which serves to divide injection fuel injected from the fuel injection port. The dividing device is formed integrally with a member in which the fuel injection port is formed and includes parallel walls substantially parallel to each other with the fuel injection port interposed therebetween and arcuate walls connected to the parallel walls having a diameter larger than that of the fuel injection port. The walls extend from said member in a direction of an axis of the valve. The dividing device has an outer diameter substantially equal to the largest diameter of the valve seat.

Electromagnetic fuel injection valve

This invention relates to an apparatus for analyzing cells in a biological liquid sample, such as blood, in which apparatus a flow passage in a sample pretreatment system can be shortened with a simple construction. A sample metering chamber, a mixing chamber and a measurement liquid extracting chamber are formed in a rotary sliding member of a pretreatment portion. The rotary sliding member is intermittently rotated so as to shift a sample from one chamber to another to perform a necessary treatment. Fluorescence or scattering light with respect to the sample, mixed with a reagent in the pretreatment portion, is detected by a flow cell.

Cell analysis apparatus

An information display apparatus which accumulates arbitrary information inputted to a television receiver from the outside, superimposes the information in a memory on an ordinary video signal and displays the superimposed image on a television display in accordance with a calender timer built in the television receiver. A remote control unit is provided for inputting information to the information display apparatus from the outside. Memories are disposed in the information display apparatus and the remote control unit for accumulating arbitrary information. A calender timer is provided for serving as a reference for displaying information are also disclosed. Arbitrary information inputted from the outside can be displayed on a television display at a previously appointed date.

Information display apparatus

A pipetter capable of mixing liquids and dispensing the mixed liquid has a pipetting tube, an actuating device connected to the tube for sucking liquid into and discharging liquid from the tube, and a flow disturbance device in the tube spaced from the discharge and suction end thereof and adapted to cause longitudinal mixing of liquid in the tube when liquid is moved along the tube in at least one direction. Mixing is effected in the tube by causing a liquid body to move repeatedly to and fro along the tube so that during each such movement at least a portion of the liquid body passes the flow disturbance device and the liquid body is not discharged from the first end of the tube. The pipetter is useful for example in mixing a suspension of blood cells with a reagent prior to analysis.

Pipetter, pipette tube, sample analyzing apparatus including them and

According to the present invention, the accuracy of particle size histograms produced from data relating to an impedance variation (Coutler Counter Method) caused by particles passing between electrodes disposed on either side of an orifice through which the particles pass is improved by excluding false data from the data used in producing the histograms, the false data resulting from more than one particle being resident in the orifice at a given data collection time. The preferred embodiment employs a light detecting method and apparatus to detect false readings and to provide correction information used to correct data obtained by the Coulter Counter Method and apparatus.

Particle analyzing method and device for realizing same

An apparatus for counting and analyzing sample particles such as cells suspended in a fluid by applying an irradiation beam such as a laser beam to the sample particles in a flow cell. The apparatus includes a device for supplying a flow cell with suspension of sample particles, an optical system for applying a laser beam to the sample particles in the above-mentioned suspension, a light gathering device for forming image of the above-mentioned sample particles, a light sensing device for sensing light from the above-mentioned formed image of the sample particles, and an analysis for analyzing the above-metnioned sample particles on the basis of the above-mentioned sensed light. The optical system may include a polarizing beam splitter and such convergent lenses having mutually different magnifications relative to two directions perpendicular to the optical axis of the laser beam.

Apparatus for counting particles suspended in a fluid having a

Particles contained in a liquid sample are analyzed by moving the particles along a detection passage past a detector using a liquid flow in the detection passage. To reduce the time required for analysis of each sample, the sample is delivered at an input location at the upstream end of the detection passage by movement of a movable container carrying the sample to the input location. Immediately after the commencement of the delivery of the liquid sample, liquid flow is caused to occur in the detection passage. Washing liquid is supplied to the input location by a liquid supplier different from the movable container which carries the sample.

Analyzing system using sheath flow of sample

A filter and filtering apparatus for measuring the deformability of a blood cell passing through a flow passage formed as a space between a surface of a groove formed in a first substrate and a surface of a second substrate with which the groove is sealed. The filtering apparatus includes electrodes mounted at the inlets and outlets of the flow passages, or optical elements to enable cell deformity measurements.

Blood filter and apparatus for hemorheological measurement

A sheath flow type flow-cell device for plow-cytometer which comprises a first inlet for sheath fluid, a flow passage communicated with the first inlet and contracted toward downstream, the flow passage having a substantially rectangular cross section, a straight capillary flow passage connected to the flow passage downstream thereof, the capillary flow passage having a substantially rectangular cross section, a second inlet for sample fluid, a nozzle communicating with the second inlet and opened within the flow passage in the same direction as the flow direction of the straight capillary flow passage, a discharge port provided at a terminal end of the straight capillary flow passage, and flow regulating means for regulating the flow of the sheath fluid in the straight capillary flow passage to be a laminar flow having a gradient of flow velocity.

Flow-cell device

A sheath flow type flow-cell device for photo-particle-analyzer comprises a substantially flat top surface, at least one first inlet for sheath fluid, at least one first flow passage communicated with the at least one first inlet and contracted toward downstream to be a straight capillary flow passage, a discharge port provided at a terminal end of the straight capillary flow passage, a second inlet for sample fluid, a second flow passage for sample fluid communicated with the second inlet and contracted toward downstream, and coupling portions for sealingly coupling with the particle photo-analyzer. The second flow passage is opened within the at least one first flow passage so as to keep a part of the at least one first flow passage above and below an opening of the second flow passage. The opening is faced in the same direction as the straight capillary flow passage. A wall portion on which the opening locates is rounded. The wall portion is further chamfered and a pair of projections are extended from the wall portion.

Sheath flow type flow-cell device

A photoanalysis apparatus includes marker pouring device for pouring markers into one of sheath fluid and fluid carrying particles in a flow-cell device, second optical device for applying a light beam for correction to the markers in the flow-cell device to measure strength of fluorescence or light scattering caused by said markers to generate a signal for correction, second signal processing device for calculating from the signal for correction at least one of a difference in position between a center of the fluid carrying particles in the flow-cell device and a center of a light beam for examination and a difference in flow rate between a predetermined flow rate and an actual flow rate of the fluid carrying particles in the flow-cell device to generate correspondingly at least one of a first command signal for position correction and a second command signal for flow rate correction, and correspondingly at least one of first correcting device for shifting the center of the light beam for examination to the center of the flow of the fluid carrying particles in accordance with the first command signal and second correcting device for correcting the flow rate of the fluid carrying particles to the predetermined flow rate in accordance with the second command signal.

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Tsuchiura, Japan

Hiroshi Ohki