Shimadzu Corporation

Hiroshi Ohashi

Hidetoshi Terada

Tadayuki Yamaguchi

Hiroshi Miura

Takayuki Kihara

Yusuke Osaka

A pH management system of a liquid chromatograph includes a pH meter that measures a pH value of a mobile phase in the liquid chromatograph, and a warner that presents a warning in a case where it is determined that a pH value measured in the pH meter is different from a set pH value, or that the pH value measured in the pH meter deviates from the set pH value and an error rate exceeds a predetermined error rate, when the pH value measured in the pH meter and the set pH are compared to each other.

PH management system of liquid chromatograph and computer readable recording medium recording program

A liquid chromatograph includes a liquid sender that sends a plurality of solvents, a mixer that has an internal capacity for mixing the plurality of solvents sent by the liquid sender, a sample injector that injects a sample into an analysis flow path through which the solvents mixed in the mixer flow as a mobile phase, a separation column provided on the analysis flow path for separating the sample injected by the sample injector to each component, a detector provided downstream of the separation column on the analysis flow path for detecting the components of the sample separated in the separation column, a capacity information storage medium that is attached to the mixer to store information as to the internal capacity of the mixer, configured to read the information stored in the capacity information storage medium to specify the internal capacity of the mixer.

Liquid chromatograph managing internal capacity of mixer

A liquid chromatograph is presented which enables automatic resolution of a liquid sending failure when the liquid sending failure caused by a liquid sending pump occurs, and execution of a new analysis with good reproducibility after the liquid sending failure is resolved. The liquid sending failure can be automatically resolved by a purging operation. A sample remaining in the analysis flow path is washed away by a non-injection analysis after the liquid sending failure is resolved, and a new analysis can be executed with good reproducibility.

Liquid chromatograph with improved defect elimination

When a flow path switch valve is in a first flow path state, an aqueous solvent supplied by an aqueous solvent supplier is guided to a first flow path, and a pH of the aqueous solvent is measured by a pH meter provided in the first flow path. When the flow path switch valve is in a second flow path state, the aqueous solvent supplied by the aqueous solvent supplier is guided to a second flow path. A sample to be analyzed is supplied by a sample supplier at a position farther downstream than the flow path switch valve. The solvent that has passed through the second flow path and the sample supplied by the sample supplier are guided to a separation column. The sample that has passed through the separation column is detected by a detector.

Liquid chromatograph and analysis execution method

A chromatograph apparatus control device according to the present disclosure is a control device for controlling a chromatograph apparatus having the function of a liquid chromatograph and that of a supercritical fluid chromatograph. The control device includes a first-type method file creator configured to create a first-type method file describing a condition of an analysis by a liquid chromatograph; a second-type method file creator configured to create a second-type method file describing a condition of an analysis by a supercritical fluid chromatograph; and a batch file creator configured to create a single batch file including a plurality of records describing a group of method files including the first-type method file and the second-type method file, with one method file in each record.

Control device for chromatograph apparatus

To reduce damage to a column caused during column switching when performing successive analyses while switching columns, provided is liquid chromatograph control systemfor analyzing a sample according to a schedule table where analysis conditions and execution order of a plurality of analyses are described. Control systemincludes: schedule readerfor reading out two consecutively executed analysis conditions; column comparatorfor comparing columns used in the two analysis conditions; insertion method file creator for creating an insertion method file so that the flow rate of a mobile phase sent to the column used in later one of the two analyses is increased in stages toward a flow rate determined for the later analysis, where the columns are different between the two analysis conditions; and a schedule table creatorfor inserting the insertion method file into immediately before the later analysis in the schedule table.

Liquid chromatograph control system and liquid chromatograph control method

The present invention aims at reducing the time required for a series of analyses in the sequential performance of gradient analyses under a variety of conditions. To this end, in a control apparatus for controlling the operation of a liquid chromatograph having a gradient analysis function in which a mobile phase composed of a plurality of mixed solvents is used and a chromatograph analysis is performed while the mixture ratio of the solvents is temporally changed, the liquid chromatograph is controlled so as to continuously change the mixture ratio of the solvents from an initial mixture ratio to a final mixture ratio when performing a sample analysis; and as to perform, before the sample analysis, a preparatory liquid supply in which the mixture ratio of the solvents is continuously changed from the initial mixture ratio to the final mixture ratio at a rate higher than that in the sample analysis.

Control system and program for liquid chromatograph

Provided is a chromatograph data processing system for presenting unexamined analysis conditions to a user in an easily understood manner when changing a plurality of analysis condition parameters. The system is used for a chromatograph for analyzing a sample according to a schedule table in which a plurality of analysis conditions and execution order of a plurality of analyses are described, each of the plurality of analysis conditions being defined by a combination of control parameter values. The system includes: memoryfor storing a plurality of analysis conditions; unexamined analysis condition creatorfor creating all combinations of values of control parameters included in the plurality of analysis conditions, and for creating a list of unexamined analysis conditions from the created combinations, the list being composed of analysis conditions that are not included in the plurality of analysis conditions stored in the memory; and display section

Chromatograph data processing system and data processing method

Provided is a liquid chromatograph control system for controlling an operation of a liquid chromatograph according to a method file containing a plurality of analysis parameters representing configuration items which determine operational conditions of the liquid chromatograph, including: a) a display section for displaying, for each of the analysis parameters, selectable values of the analysis parameter on a condition-setting screen; b) a grouping section for allowing a user to prepare grouping information for the values of the analysis parameter displayed on the condition-setting screen, the grouping information determining whether or not one value of one analysis parameter and one value of another analysis parameter can be included in one group; and c) a file-creating section for extracting, from the values of the analysis parameters, such values that can be included in one group according to the grouping information, and for creating a method file containing the extracted values.

System and method for controlling liquid chromatograph

A liquid chromatograph analysis method and a liquid chromatograph minimize analysis time when performing analyses by switching columns and mobile phases. Liquid chromatographfor performing a plurality of analyses according to a schedule table includes: mobile phase switching sectionsfor switching a plurality of mobile phases to select a mobile phase to be used in analysis; column switching sectionsfor switching a plurality of columns-to select a column to be used in analysis; and control sectionincluding memoryfor storing an equilibration time of each of the plurality of columnstoand an equilibration controllerfor controlling column equilibration. If used columns or used mobile phases are different between two consecutively executed analyses, equilibration controllerequilibrates a column used in the later of the two analyses over an equilibration time read out from memory

Liquid chromatograph and liquid chromatograph analysis method

A liquid chromatograph control system for controlling an operation of a liquid chromatograph which uses a mobile phase composed of a mixture of solvents and which has the function of performing a gradient analysis while temporally changing the mixture ratio of the solvents. The system initially requests a user to set a basic gradient profile (Step S), and subsequently, to set the number of steps to change the mixture ratio of the mobile phase at the beginning and/or at the end of the gradient process as well as the amount of change in the mixture ratio per step (Step S). After that, based on the possible combinations of the mixture ratios of the mobile phase at the beginning and at the end of the gradient process computed from the contents of information entered in the previous steps, a plurality of gradient profiles corresponding to those combinations are created (Step S).

Growing community of inventors

Otsu, Japan

Hiroshi Ohashi