Kao Corporation

Taiyo Kagaku Co., Ltd.

Fudan University

Hiroshi Nojiri

Sachio Naito

Hidehisa Takahashi

Genji Imokawa

Chun Yang

Kimihiko Hori

Michitaka Sawada

Shotaro Ito

Hiroyuki Yanagida

Mami Nonomura

Takashi Koyama

Mujo Kim

Masaru Fujiki

Kazuyo Watanabe

Kozo Arai

Toshiki Kobayashi

Fumiko Okuda

Fan Qi Kong

Wan Zhang Qin

Chun Xin Yang

The present invention provides a pharmaceutical composition or a cosmetic product which can accelerate production of ceramide in cells. The ceramide production-accelerating agent contains a plant selected from the group consisting of, and, or an extract thereof as an active ingredient. Further, the present invention provides a moisturizing agent containing a plant selected from the group consisting ofand, or an extract thereof as an active ingredient.

Ceramide production-accelerating agent

An allergen inactivating agent is provided which has no adverse effects on the human body and which does not cause problems such as color development. An allergen inactivating agent containing a polysaccharide derivative as its effective component, wherein said polysaccharide derivative has a cellulose ether or a starch ether as its backbone, and some or all of hydrogen atoms in the hydroxy group of the polysaccharide derivative are substituted by a group represented by the following general formula (1):-E-(OA)-E-R&#x2003;&#x2003;(1)wherein Erepresents an alkylene containing 1 to 6 carbon atoms optionally substituted with hydroxy group or oxo group; n represents a number of 0 to 50; A independently represents an alkylene containing 1 to 6 carbon atoms, the number of A being n; Erepresents ether bond or oxycarbonyl group; R represents an alkyl group containing 4 to 30 carbon atoms optionally substituted with hydroxy group, a sulfoalkyl group containing 1 to 5 carbon atoms optionally substituted with hydroxy group, or a salt thereof.

Allergen inactivating agent

The present invention provides a hair cosmetic composition containing an antibody (a) to hair or a hair extract obtained from egg yolk of poultry immunized with the hair or hair extract, and a polymer emulsion (b). The hair cosmetic composition of the invention can provide excellent properties including softness, moistened feel, and smoothness. In addition, since it is adsorbed only onto a specified part of the hair, stickiness or greasiness of the hair can be prevented. The composition also prevents occurrence of split hairs, and even repair the split hairs. These effects are not lost by repeated ordinary shampooings.

Hair cosmetic composition

A hair care product contains a yolk antibody (a yolk-derived, anti-hair antibody) which has been obtained from an egg of a domestic fowl immunized using, as an antigen, whole human hair, e.g., normal human hair or human hair damaged by permanent waving, dyeing or bleaching, hair particles obtained by grinding constituent tissues of human hair, the keratin protein extracted from the human hair, or a hydrolysate of the keratin protein.

Yolk antibody-containing hair care product

A process for the production of a solubilized protein is disclosed, which is obtained by reducing disulfide bonds in a disulfide bond-containing water-insoluble protein material into mercapto groups and subsequently converting a part or an entire portion thereof into carboxymethyldisulfide groups. In particular, the disclosed process for the production of a solubilized protein which comprises (a) treating a disulfide bond-containing water-insoluble protein material with an aqueous alkaline solution of a reducing agent, and (b) reacting the protein treated by step (a) with thioglycolic acid in the presence of an oxidizing agent under a weakly acidic to a weakly alkaline condition. A process for the production of regenerated protein products, which comprises regenerating disulfide bonds in the solubilized protein, is also disclosed.

Process for producing solubilized protein

Growing community of inventors

Tokyo, Japan

Hiroshi Nojiri