Kowa Company Limited

Hiroshi Nakao

Takao Nagoya

Makoto Suda

Seiichi Sato

Hiroyuki Ishiwata

Mototsugu Kabeya

Soichi Oda

Manabu Shibasaki

Yukio Hattori

Masami Shiratsuchi

Yushi Saino

Hiromichi Shigyo

Takaharu Asano

Katsumi Yabusaki

Muneharu Ishikawa

Masahiro Maki

Hideo Tani

Michihisa Umetani

Diamide compound and medicine containing the same

A method of measuring the number of times of a specific behavior of an animal in a breeding cage comprising a step in which a common pattern of the specific behavior is determined by receiving a signal of vibration of the cage caused by the specific behavior of the animal and extracting the feature of a frequency component of the signal, a step in which a measurement objective pattern is determined in the same way, and a step in which the common patterns in the measurement objective patterns is counted; a device for the measurement including means for detecting the vibration of the breeding cage, means for extracting the feature of the frequency component, and means for counting the common patterns in the measurement objective patterns; and a method for measuring the specific behavior such as a scratching of a small animal, e.g., a mouse in a breeding cage noninvasively, and an automatic measuring instrument.

Method and device for measuring frequency of specific behavior of animal

Cyclic amide compound

Diamide compounds and compositions containing the same

Provided are a method, upon radical copolymerization of a vinyl-containing porphyrin compound and a radically polymerizable monomer, thereby obtaining a porphyrin-nucleus introduced polymer, of controlling reactivity of the porphyrin-nucleus introduced polymer with a metal by selecting the radically polymerizable monomer; and a method for measuring a trace metal by measuring a change in absorbance caused by a complex forming reaction between a porphyrin-nucleus introduced polymer, which has been obtained by radical copolymerization of a vinyl-containing porphyrin compound and a radically polymerizable monomer, and a heavy metal ion, the radically polymerizable monomer being selected so as to heighten reaction selectivity of the porphyrin-nucleus introduced polymer to a metal to be measured. The present invention makes it possible to control the properties or reactivity of the porphyrin-nucleus introduced polymers, which have been obtained from easily available porphyrin compounds without any modification, and by making use of this technique, to provide a highly sensitive method for measuring heavy metals.

Trace metal measuring method

Cyclic amide compounds

Porphyrin-nucleus introduced polymers

Diamide compound and drugs containing the same

The present invention relates to compounds represented by the following general formula (1):

The present invention is directed to a cell adhesion inhibitory agent, cellular infiltration inhibitory agent, antiallergic agent, antiasthmatic agent, and antiphlogistic, which contains a compound of the following formula (1): ##STR1## wherein each of R.sup.1 through R.sup.6 represents H, a halogen atom, a hydroxyl group, a lower alkyl group, or a lower alkoxy group, m represents a number of 1 from 3 inclusive, and n represents 2 or 3.

Inhibitors for cell adhesion and cellular infiltration

Therapeutic agent for skin or corneal disease

A monoclonal antibody specific to a human placenta-derived coagulation inhibitor is disclosed. The antibody is produced by culturing a hybridoma which secretes it. A human placenta-derived coagulation inhibitor can be purified by using the monoclonal antibody as an immunoadsorbent. The human placenta-derived coagulation inhibitor can be immunologically assayed by using the monoclonal antibodies.

Placenta-derived coagulation inhibitor

Anti-PCI monoclonal antibody

Growing community of inventors

Tsuchiura, Japan

Hiroshi Nakao