Shiseido Company, Limited

Hiroshi Kutsuna

Kazuyuki Miyazawa

Yukimitsu Suda

Taketoshi Kanda

Masayoshi Wada

Kenichi Sakuma

Yousuke Toujo

Hiroshi Fukui

Michihiro Yamaguchi

Yutaka Ohtsu

Tsuneo Suhara

Yoshihiro Shiojima

A phosphorylcholine group-containing chemical compound represented by the following formula (1): 

Phosphorylcholine group-containing compound and surface modifying agent composed of such compound

A phosphorylcholine group-containing chemical compound represented by the following formula (1).  In this formula, m denotes 2-6 and n denotes 1-4. X, X, and X, independent of each other, denote a methoxy group, ethoxy group, or halogen. Up to two of X, X, and Xcan be any of the following groups: a methyl group, ethyl group, propyl group, isopropyl group, butyl group, or isobutyl group. R is one of the structures in the following formulas (2)-(4) (the chemical compound of formula (1) in the structures of the following formulas (2)-(4) is expressed as A-R&#x2014;B).  In formulas (2)-(4), L is 1-6, P is 1-3. Also a surface modifier consisting of the aforementioned phosphorylcholine group-containing chemical compound, modified powder treated with said surface modifier, a chromatography packing consisting of a modified carrier treated with said surface modifier, a filter treated with said surface modifier, and a glass device treated with said surface modifier.

Phosphorylcholine group containing compound and surface modifying agent composed of such compound

A packing material for liquid chromatography bears a polyalkylene polyamine moiety linked through a spacer moiety as the pendant group to a porous silica gel coated with a silicone polymer, and optionally is crosslinked by a crosslinking agent on two or more amino group of the different polyalkylene polyamine moieties, and a process for production thereof. Such a packing material is especially useful in the analysis of sugars.

Packing material for liquid chromatography

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Yokohama, Japan

Hiroshi Kutsuna