Dai Nippon Printing Co., Ltd.

Dai Nippon Insatsu Kabushiki Kaisha

Teijin Pharma Limited

Central Glass Company, Limited

Merck Sharp + Dohme Corp.

Gunma University

Adv Antest Corporation

Oki Data Corporation

Teijin Limited

Mitsui Toatsu Chemicals, Incorporated

Oki Electric Industry Co., Ltd.

Osaka City University

University Public Corporation Osaka

Merck Sharp & Dohme LLC

Hiroshi H Eguchi

Masayuki M Nakamura

Hitoshi Saito

Jumpei J Kanto

Ryohei Takiguchi

Komei Kafuku

Hideaki Sato

Akira Tanokura

Naoko Namiki

Koumei Kafuku

Mineo M Yamauchi

Takashi Murakami

Kazuya Yoshida

Jeanne E Baker

Minoru M Furuse

Carl Mieczkowski

Sophie Parmentier Batteur

Gopalan (Raghu) Raghunathan

Masatomo Mori

Angela Marie Jablonski

Daniel Stephen Malashock

Katsuyuki Oshima

Kazuhiro Yamanaka

Keisuke Takuma

Masanori Yamamoto

Kazunobu Imoto

Takeshi Ueno

Hideo H Fujimura

Mikio Asajima

Kazuo Sakamoto

Hitoshi Koshida

Tsukasa Ohyama

Satoru Kawai

Yoriaki Matsuzaki

Isamu Ghoda

Junya Nakatsuji

Kenji Hosoi

Emi Matsuba

Kenichiro Takagi

Kensuke Hirotaki

Yasushi Shimokawa

Hiroyuki Shimizu

Hirotsugu Kato

Satoshi Yamamura

Yosuke Murakami

Hiroto Hori

Kaoru Suda

Eiichi Yada

Junji Chiba

Katsuhiro Akiyama

Yusuke Nakamura

Masanori Akada

Yuichi Kunori

Mitsuhiro Oota

Yasushi Yoneyama

Kenichi Masuda

Shigeo Yasui

Kei Matsunaga

Hirofumi Higuchi

Kenichi Aso

Tsuyoshi Ogawa

Masayuki Tani

Yukari Hara

Nobuyuki Harada

Ayashi Noguchi

Kazuyoshi Yamaoka

Takeshi Suda

Kenichiro Sudo

Yue Yu

Masashi Ono

Ayumi Yamaguchi

Masanori Okuda

Susumu Yasuoka

Yu Matsuno

Daisuke Ishikawa

Masayo Ohori

Tomoyo Takeo

Wataru Kawai

Yoichi Matsumoto

Hiroshi Mori

Takami Tomiyama

The present invention has the effect of making it possible to produce 1,1,1-trifluoro-2,2-bisarylethane efficiently by a simple procedure by condensing a mixture of fluoral and hydrogen fluoride with an aryl compound under anhydrous conditions. The purity of the 1,1, 1-trifluoro-2, 2-bisarylethane obtained can be raised by a simple purification method such as crystallization or distillation. The obtained 1,1,1-trifluoro-2,2-bisarylethane can be increased in purity by a simple purification method such as crystallization operation or distillation.

Method for producing 1,1,1-trifluoro-2,2-bisarylethane, and 1,1,1-trifluoro-2,2-bisarylethane

A polyimide which is obtained by a reaction of an aromatic diamine having a 1,1,1-trifluoro-2,2-ethanediyl group (—C(CF)H—), as a linkage skeleton, with a tetracarboxylic dianhydride is easily dissolved in an organic solvent and exhibits excellent film forming properties. In addition, the thus-obtained polyimide can be used for an optical film and a display device.

Polyamide acid, polyimide, optical film, display device and production methods thereof

A thermal transfer sheet according to the present disclosure includes a first substrate and a metallic luster layer containing a metal pigment, the metallic luster layer having a 45-degree specular gloss in the range of 30% to 80%.

Thermal transfer sheet, combination of thermal transfer sheet and intermediate transfer medium, and method for producing printed material

Provided is a thermal transfer sheet with low hot and cold peeling strengths. Thermal transfer sheet according to the present disclosure includes a substrate and a transfer layer, wherein the transfer layer includes at least a peeling layer, and the peeling layer contains a vinyl resin and at least one of an alcohol alkoxylate and an alcohol having 18 to 80 carbon atoms.

Thermal transfer sheet

A thermal transfer sheet includes a substrate and a transfer layer, in which the transfer layer after transfer has a reduced peak height (Spk) of 0.6 μm or more. A method for producing a printed material using a thermal transfer sheet including a particle layer disposed on a substrate and an image-receiving sheet including a thermal protrusion-and/or-recess forming layer and a receiving layer stacked in that order on a second substrate, the receiving layer including an image that has been formed, includes the steps of heating the image-receiving sheet to form a protrusion and/or a recess at the image-receiving sheet, and heating the thermal transfer sheet to transfer the particle layer to at least part of the protrusion of the image-receiving sheet.

Thermal transfer sheet and method for producing printed material

Provided is a humanized antibody that, through IGF-I receptor, increases muscle mass but does not lower the blood glucose level. This humanized antibody: is an anti-IGF-I receptor humanized antibody, a fragment thereof, or a derivative thereof; has a specific amino acid sequence such as SEQ ID NOs: 1 to 6 serving as a CDR sequence; and specifically binds to IGF-I receptor extracellular domain.

Anti-IGF-I receptor humanized antibody

The invention provides methods for using and compositions of humanized antibodies that bind tau protein that is phosphorylated at the serine at position 413.

Humanized antibody for treating or preventing cognitive disorders, process for producing the same, and agent for treating or preventing cognitive disorders using the same

The present invention provides an anti-IGF-I receptor antibody that binds specifically to an IGF-I receptor of a vertebrate and has the proliferation-inducing activity of a vertebrate-derived cell, or a fragment thereof, or derivatives of these.

Anti-IGF-I receptor antibodies, encoding nucleic acid molecules and methods of using said antibodies

An image forming apparatus includes: a memory configured to store identification information identifying an information terminal device and mode information indicating a mode corresponding to the information terminal device in association with each other; a communication interface configured to receive from the information terminal device a wireless signal including identification information that is stored in the information terminal device and identifies the information terminal device, and determine an intensity of the received wireless signal; and a controller configured to, when determining that the determined intensity of the received wireless signal is equal to or greater than a predetermined intensity, read from the memory the mode information corresponding to the identification information included in the received wireless signal, and set the image forming apparatus to the mode indicated by the read mode information.

Image forming apparatus, method for setting apparatus, and computer-readable medium

Disclosed is a curable composition including a silicone (A) of a specific structure and a composition containing Si&#x2014;OH group and Si&#x2014;H group, a silicone (B) of a specific structure and a composition containing Si&#x2014;OH group and Si&#x2014;CH&#x2550;CHgroup, and a hydrosilylation catalyst of a catalytic quantity containing at least one metal compound selected from the group consisting of platinum compounds, palladium compounds, and rhodium compounds. In this curable composition, as kind of each silicone and the content of Si&#x2014;OH group are adjusted, in curing the silicone, foaming in a cured product can be inhibited by inhibiting a dehydration condensation reaction between Si&#x2014;OH groups, as compared with a hydrosilylation reaction which is a reaction of Si&#x2014;CH&#x2550;CHgroup and Si&#x2014;H group. Furthermore, an excellent adhesion to a base body such as semiconductor substrate can be given when making a cured film.

Curable composition containing silicone, and cured product thereof

A composition containing a metal compound and a siloxane compound (A) represented by general formula (1): wherein X is represented by general formula X1 or X2: wherein the number of X1 is 1-8; the number of X2 is 0-7; the sum of the number of X1 and the number of X2 is 8; Rto Rrepresent a hydrogen atom, a Calkyl group, alkenyl group, alkynyl group, or a Caryl group, a hydrogen atom thereof optionally being substituted by a fluorine atom; Rrepresents a Calkyl group, alkenyl group, alkynyl group or aryl group, a hydrogen atom thereof being optionally substituted by a fluorine atom, a carbon atom being optionally substituted by an oxygen atom or a nitrogen atom; Rrepresents a hydrogen atom, a vinyl group or an allyl group; m and n represent an integer of 1-4; and 3&#x2266;m+n.

Siloxane-based composition and cured product thereof, and use therefor

The present invention relates to a novel method of obtaining a factor involved in appetite control and/or body weight control, as well as genes obtained by said method, polypeptides encoded by said genes, or novel polypeptides obtained from the information on polypeptides encoded by said genes as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control. Also the present invention relates to substances that inhibit the effects of said genes or said polypeptides as a means for treating, controlling or diagnosing diseases associated with appetite control and/or body weight control. By using thiazolidine diones having a PPAR &#x3b3; agonist activity, genes and polypeptides involved in appetite regulation and/or body weight reduction can be obtained. NESFATIN or the like obtained by said method can be used as a means for treating, controlling or diagnosing diseases associated with eating disorders and/or body weight control.

Biological substance nesfatin and its related substances and uses thereof

An object of the present invention is to identify a Nesfatin-1 receptor, and to provide a method for screening or designing a Nesfatin-1-action regulating substance or a Nesfatin-1-like action substance using the Nesfatin-1 receptor. A method for screening a Nesfatin-1-like action substance comprising steps of making a test substance act on a receptor protein selected from the group consisting of GPR3, GPR6 and GPR12, and of identifying the Nesfatin-1-like action substance based on a change of Nesfatin-1 action.

Screening GPR12 receptor for substances having Nesfatin-1-like action, or which regulate Nesfatin-1 action

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Tokyo, Japan

Hiroshi H Eguchi