Takeda Pharmaceutical Company Limited

Takeda Chemical Industries, Inc.

Hiroshi Fukada

Tetsuro Tabata

Hikaru Fukuyama

Toshihide Saito

Toshihiro Shimizu

Shigeyuki Marunaka

Shigehiro Higuchi

Norio Kameoka

Etsuji Nakamura

The present invention provides a method for treating a solid dosage form to improve the printability and abrasion resistance of a print to be produced on a surface of the solid dosage form, which includes treating the surface of the solid dosage form with a polyethylene glycol-containing aqueous solution before printing; a production method of a solid dosage form with a printed surface, which includes printing on the surface after the aforementioned treatment; and a solid dosage form having a print improved in abrasion resistance on its surface, which can be obtained by the aforementioned production method.

Method for treatment of solid pharmaceutical preparation prior to printing and solid pharmaceutical preparation subjected to treatment prior to printing

It is intended to provide a method of producing a solid preparation disintegrating in the oral cavity characterized by comprising mixing fine subtilaes containing a medicinal ingredient with an additive containing &#x3b4;-mannitol and tableting the mixture; and a solid preparation disintegrating in the oral cavity produced thereby. This solid preparation disintegrating in the oral cavity has such a strength (hardness) as suffering from no defect even under stresses in transporting, packaging with the use of an automated packaging machine, taking out from a PTP and soon.

Method of producing solid preparation disintegrating in the oral cavity

The punch coated with Cr-Dop&eacute;-N is advantageous as a punch for preparing tablets containing an acidic substance or an adhesive substance and is excellent in corrosion resistance and releasing property.

Compressing mallet with coating treatment

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Osaka, Japan

Hiroshi Fukada