Johns Hopkins University

Siemens Healthcare Gmbh

Hiroshi Ashikaga

Tommaso Mansi

Henry R Halperin

Bin Lou

Julian Krebs

Tomohiro Otani

Katherine Chih-ching Wu

Systems and methods for personalized sudden cardiac death risk prediction that generates fingerprints of imaging features of cardiac structure and function. One or more fingerprints and clinical data may be used to generate a risk score. The output risk score may be used to predict the time of death in order to select high-risk patients for implantable cardioverter-defibrillator treatment.

Risk prediction for sudden cardiac death from image derived cardiac motion and structure features

The present application relates to systems and methods for performing a computerized cardiac simulation for at least one of diagnosis, risk assessment or treatment planning including: receiving, by a computer, a plurality of three-dimensional cardiac images of a subject's heart such that each three-dimensional cardiac image corresponds to a different phase of a single cardiac cycle of the subject's heart; modeling structure, using the computer, of the left atrium of the subject as a function of time using the plurality of three-dimensional cardiac images of the subject's heart; modeling blood flow, using the computer, within, into and out of the left atrium of the subject as a function of time using computational fluidic dynamics and using structure of said left atrium obtained from at least one of said plurality of three-dimensional cardiac images or said modeling structure of said left atrium; simulating at least one of time dependent structural function or time-dependent blood flow of said left atrium using results from said modeling structure and said modeling blood flow for a selected period of time; and providing information to a user from said simulating for use in at least one of diagnosis, risk assessment or treatment planning for a physiological effect related to function of said left atrium of the subject.

Patient-specific virtual intervention laboratory to prevent stroke

Growing community of inventors

Lutherville Timonium, MD, United States of America

Hiroshi Ashikaga