Nippon Kayaku Kabushiki Kaisha

Hiroshi Akanuma

Masahiko Yabuuchi

Tsuneo Nakamura

Minoru Masuda

Masashi Hashiba

Shigeru Tajima

Hiroshi Hayami

Kazuo Katoh

Kazuo Kato

Masachika Hirayama

Tomoko Takezawa

Akira Takahashi

Akinori Naito

A present invention relates to a method for quantitatively determining sugar-alcohols characterized by passing test samples containing sugar-alcohols, proteins, and saccharides through a column filled with basic anion-exchange resins which have a protein-removing ability and a saccharide-removing ability, and then quantitaing the sugar-alcohols in the effluent out of the column, a column filled with said resins and an aqueous solution of boric acid, and a kit. Sugar-alcohols such as 1,5-anhydroglucitol and the like have been calling attention as markers for diabetes mellitus recently.

Method for quantitatively measuring sugar-alcohol, column and kit

This invention relates to a novel method for assaying 1,5-anhydroglucitol, which is expected to serve as a marker for diabetes, and a kit therefor. More particularly, it relates to:

Method for assaying 1,5-anhydroglucitol and kit therefor

The present invention relates to a method of quantitative assay for 1,5-anhydroglucitol which comprises oxidizing 1,5-anhydroglucitol in an aqueous solution of a specimen in the presence of an electron acceptor to produce a compound represented by formula (1) below or a hydrate thereof represented by formula (2) below and quantitatively determining 1,5-anhydroglucitol from a consumption amount of said electron acceptor in said aqueous solution of a specimen or from a production amount of the reduction product of said electron acceptor produced or from an amount of oxidized product of 1,5-AG represented by formula (1) or formula (2). ##STR1##

Method of quantitative assay for 1,5-anhydroglucitol

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Yokohama, Japan

Hiroshi Akanuma