Kaken Pharmaceutical Company, Ltd.

Hironobu Ogura

Tadashi Arika

Mamoru Yokoo

Takanobu Naito

Tokiko Nishida

Kiyoshi Nagai

Satoko Shusse

Haruhito Kobayashi

Yoshiyuki Tatsumi

Yuji Fukamizu

An azolylmethylidenehydrazine derivative represented by the formula (I) wherein Ar is an aryl group optionally having substituent(s) or a heteroaryl group optionally having substituent(s), Rand Rare the same or different and each is an alkyl group, a cycloalkyl group, an aralkyl group optionally having substituent(s), an aryl group optionally having substituent(s), a heteroarylalkyl group optionally having substituent(s), or Rand Rare bonded to each other to form a nitrogen-containing heterocyclic group optionally having substituent(s), and X is CH or a nitrogen atom, or a pharmacologically acceptable salt thereof is useful as a medicament, particularly as an antifungal agent, or an anti-inflammatory agent or an antiallergic agent.

Azolylmethylidenehydrazine derivative and use thereof

There is disclosed a fungicide containing, as an effective ingredient, a compound having the general formula (I): ##STR1## or an acid addition salt thereof, particularly the compound wherein an absolute configuration of the asymmetric carbon atoms is R,R-configuration or an acid addition salt thereof.

Azolylamine derivative

There is disclosed a fungicide containing, effective ingredient, a compound having the general formula (I): ##STR1## or an acid addition salt thereof, particularly the compound wherein an absolute configuration of the asymmetric carbon atoms is R,R-configuration or an acid addition salt thereof.

Growing community of inventors

Kyoto, Japan

Hironobu Ogura