Ajinomoto Co., Ltd.

Tokyo Institute of Technology

Hiromi Noguchi

Hideo Hosono

Hiroyuki Kojima

Toshiharu Yokoyama

Michikazu Hara

Masaaki Kitano

Kazuteru Yamada

Mitsuhiro Kishino

Toru Numaguchi

Munenobu Ito

Yoshihiro Ito

Yoshihiko Hara

Hiroshi Izui

Yo Nishiyama

Provided is a novel production system that does not involve, or can minimize, the transport of liquid ammonia in the production of an organic compound or the production of a microorganism by microbial fermentation. A production system for an organic compound or a microorganism includes: an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported ruthenium catalyst; and a culture apparatus that cultures a microorganism having organic compound productivity using ammonia originating from the ammonia-containing gas obtained by using the ammonia synthesis apparatus.

Production system and method of production for organic compound or microorganism

A production system for a product selected from a nitrogen-containing product and a fermented and cultured product that does not involve (or can minimize) the transport of liquid ammonia can include: an ammonia synthesis apparatus in which an ammonia-containing gas is synthesized by reaction of a source gas containing hydrogen and nitrogen in the presence of a supported metal catalyst containing as a support one or more selected from the group consisting of: i) a conductive mayenite compound; ii) a two-dimensional electride compound or a precursor thereof; and iii) a complex formed of a support base containing at least one metal oxide selected from ZrO, TiO, CeO, and MgO and a metal amide represented by a formula M(NH)(where M represents one or more selected from Li, Na, K, Be, Mg, Ca, Sr, Ba, and Eu; and x represents a valence number of M) supported by the support base.

Production system and method of production for product selected from nitrogen-containing product and fermented and cultured product

A method for producing an L-amino acid such as L-glutamic acid is provided. An L-amino acid is produced by culturing in a medium a bacterium having an L-amino acid-producing ability, which has been modified so that the activity of a c1795 protein is reduced or the activity of a protein of which the expression is repressed by a c1795 protein is increased, and collecting the L-amino acid from the medium or cells of the bacterium.

Method for producing L-amino acid

A gene isolated from a microorganism selected from the group consisting ofbacteria,bacteria, andbacteria, and encoding a Rep protein or a homologue thereof is described. A plasmid containing the gene which is autonomously replicable in Enterobacteriaceae bacteria is also described. A Enterobacteriaceae microorganism containing the plasmid is also described.

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Kanagawa, Japan

Hiromi Noguchi