Nippon Soda Co., Ltd.

Hiromi Horikoshi

Nobuhiro Umeda

Nobuo Mochizuki

Seiichi Uchida

Hirokazu Yamada

Yasuyuki Shiinoki

Tadayuki Nishibe

Kunihito Ito

Thienopyrimidine compounds and salts thereof and process for the preparation of the same

Phenylazole compounds represented by general formula (1) or pharmaceutically acceptable salts thereof and drugs for hyperlipemia which contain these compounds as the active ingredient, wherein A represents imidazolyl, pyrazolyl, etc.; B represents (1 ) or (1 ) (wherein R and R represent each hydrogen, C alkyl, etc; and k is 0 or an integer of 1 to 15); Y represents O, S, a bond, etc.; and Z represents an optionally substituted and saturated or unsaturated heterocycle containing 1 to 4 N, O or S atoms. Among all, compounds wherein Z is substituted chroman-2-yl, 2,3-dihydrobenzofuran-2-yl, etc. have an effect of inhibiting the formation of lipid peroxides too.

Phenylazole compounds, process for producing the same and drugs for hyperlipemia

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Hokkaido, Japan

Hiromi Horikoshi