Shikoku Chemicals Corporation

Hiroko Yabe

Takayuki Fujita

Yoshiya Iwasaki

Tadashi Akita

Disclosed is a novel imidazole compound represented by the following formula: ##STR1## wherein A.sub.1 stands for a thien-3-yl or 4-chlorophenyl group and A.sub.2 stands for a 2,4-dichlorophenyl, 2-chlorothien-3-yl or 2-chloro-5-bromothien-3-yl group, with the proviso that at least one of A.sub.1 and A.sub.2 stands for a thien-3-yl or halogen-substituted thien-3-yl group. This compound is effective as a therapeutic antifungal agent or mildewproofing agent.

Antifungal and mildewproofing imidazole compounds

1-(4-Chlorophenyl)-2-(1H-imidazolyl)-3-(2,4-dichlorophenyl)-2-propen-1-one hydrochloride is useful as a chemotherapeutant which is administered to men or animals for remedy of diseases caused by true fungi or bacteria.

Chemotherapeutant composition

Disclosed are compounds represented by the following general formula and its hydrochloride salts: ##STR1## wherein A.sub.1 stands for a phenyl group, a halophenyl group, a thienyl group or a halothienyl group, and A.sub.2 stands for a phenyl group or a halophenyl group. These compounds can be obtained by reacting an imidazole compound of the following formula: ##STR2## with a benzaldehyde compound of the formula A.sub.2 -CHO. These compounds are valuable as fungicidal agents.

Growing community of inventors

Tokushima, Japan

Hiroko Yabe