Riken Corporation

Juntendo Educational Foundation

Kanagawa Prefectural Hospital Organization

Hiroko Oomiya

Yoshihide Hayashizaki

Takashi Ohtsu

Satoru Takeda

Masayoshi Ito

Kieko Hara

Hideya Kawaji

Yasunari Yamanaka

Kenji Suzuki

Keiko Mitani

Kaoru Mogushi

Kazuya Takamochi

Tsuyoshi Saito

Yasuhisa Terao

Yohei Miyagi

Hisamori Kato

Provided is an approach for differentially determining the histological type of a lung cancer lesion objectively and rapidly with high accuracy. A method for differentially assessing a lesion in a lung cancer patient as squamous cell carcinoma or adenocarcinoma, comprising a step of measuring an expression level of an expression product of at least one DNA comprising a transcription start site in a biological sample collected from the lesion, wherein the DNA comprises a base at an arbitrary position in the transcription start site and at least one or more bases located immediately downstream thereof in any of nucleotide sequences represented by SEQ ID NOs: 1 to 213, and the transcription start site is a region wherein both ends thereof are defined by the first base and the 101st base counted from the 3' end in any of the nucleotide sequences represented by SEQ ID NOs: 1 to 213.

Method for differentiating between lung squamous cell carcinoma and lung adenocarcinoma

Growing community of inventors

Wako, Japan

Hiroko Oomiya