Kyowa Hakko Kogyo Co., Ltd.

Hiroko Akita

Takayuki Uwajima

Osamu Terada

Kazuo Aisaka

Yoshiaki Shimizu

Akira Mihara

Toshiaki Nagai

Glycerol oxidase is an oxidizing enzyme of glycerol characterized by its ability to oxidize glycerol in the presence of oxygen to form hydrogen peroxide and glyceraldehyde. This enzyme is produced by cultivation of a microorganism belonging to the genus Aspergillus or the genus Neurospora in a nutrient medium.

Glycerol oxidase and process for the production thereof and method for

Glycerol oxidase II is an oxidizing enzyme of glycerol characterized by its ability to oxidize glycerol in the presence of oxygen to form hydrogen peroxide and glyceraldehyde. This action of the present enzyme is the same as that of the enzyme glycerol oxidase I disclosed in U.S. application Ser. No. 897,695 filed on Apr. 19, 1978. However, this enzyme has characteristic properties in substrate specificity, optimum and stable pH, optimum temperature for action, substrate affinity (Michaelis constant glycerol). This enzyme is produced by culturing a microorganism belonging to the genus Penicillium.

Glycerol oxidase and process for the production thereof

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Yokohama, Japan

Hiroko Akita