National Institute of Advanced Industrial Science and Technology

Neo-morgan Laboratory Incorporated

Hiroko Abe

Yasunori Chiba

Kenichi Nakayama

Yoshihiro Nakajima

Yoshifumi Jigami

Shohei Yamamura

Masatoshi Kataoka

Shouki Yatsushiro

Tomoko Iwaki

Yuki Takaoka

Kazuya Tomimoto

Akiko Itadani

Yasuko Fujita

The present invention provides: genetically modified yeasts such as mutant yeasts having an ability to produce N-linked sugar chains of ManGlcNAcand a decreased ability to produce O-linked sugar chains, mutant yeasts having an ability to produce N-linked sugar chains of ManGlcNAcand further having an ability to produce N-linked sugar chains of GlcNAcManGlcNAc, and mutant yeasts having an increased ability to produce and secrete proteins and an ability to produce N-linked sugar chains of ManGlcNAc; and a method for producing glycoproteins using them.

Sugar-chain modified yeast and method for producing glycoprotein using the same

A method for breeding yeast having thermotolerance or recovering growth activity and a method for breeding yeast which produces beta-glucan efficiently as well as an yeast obtained by such methods for breeding are presented by a method for breeding yeast having thermotolerance or recovering growth activity including a step for controlling proofreading function of DNA polymerase in a loss-of-function mutant of yeast (for example, a step for including mutant pol3 gene or mutant cdc6&#x2212; gene in a gene-disruptant.

Breeding method for yeast, yeast and a production method for glycoprotein or beta-glucan

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Kagawa, Japan

Hiroko Abe