Sekisui Chemical Co., Ltd.

Hiroki Iguchi

Satoshi Haneda

Ryoma Ishii

Yuriko Manabe

Hiroshi Yamauchi

Takahiro Omura

Yuuhei Arai

Yuuta Nakamura

Yuhei Arai

Provided is a cell culture scaffold capable of allowing cell masses to be formed easily and efficiently. A cell culture scaffold according to the present invention includes a substrate; and a protrusion formed by patterning in a pattern of a dot or a line on the substrate, wherein the protrusion contains a synthetic resin, the synthetic resin contains at least a polyvinyl alcohol derivative or a poly(meth)acrylic resin, the protrusion has cell adhesion, and a portion of the protrusion located at the protrusion center position in plan view has an average height of 10 nm or more and 10 μm or less.

Scaffold material for cell culture and cell culture container

A scaffold material for cell culture having excellent cell colonization is provided. A scaffold material for cell culture according to the present invention includes a synthetic resin having a main chain and a graft chain, wherein the graft chain has a polydentate hydrogen-bonding group represented by the following formula (1) in a side chain: *—R-(A)(1) wherein R represents a group having 50 or less carbon atoms, Arepresents an amino group, a carboxyl group, a hydroxyl group, a sulfone group, an imino group, or a thiol group, i represents a natural number, n represents an integer of two or more and four or less, and * represents a bonding position with another atom constituting the graft chain; and Amay be identical or different from each other.

A scaffolding material for culturing a stem cell, which contains a synthetic resin, and has

Scaffolding material for stem cell cultures and stem cell culture method using same

Provided is a resin film having excellent cell extensibility in cell culture. The resin film formed of a scaffold material for cell culture containing a synthetic resin, the resin film having a compressive modulus of 5.5 GPa or more at a frequency of 1 Hz as measured using a nanoindenter device in ion-exchanged water in accordance with ISO14577-1 after being immersed in the ion-exchanged water at 37° C. for 24 hours.

Resin film formed by scaffold material for cell culture and container for cell culture

A scaffolding material for stem cell culture, which has a dispersion component γof the surface free energy of 24.5 or more and less than 45.0, and a dipole component γof the surface free energy of 1 or more and less than 20.0. According to the scaffolding material for stem cell culture, the scaffolding material can have suitable hydrophilicity and strength, high fixation of stem cells after seeding, and highly efficient cell proliferation.

A scaffolding material for culturing a cell, the scaffolding material for culturing a cell containing a synthetic resin, and having a nitrogen content of the synthetic resin of 0.1% by mass or more and 10% by mass or less. According to the scaffolding material for cell culture, the scaffolding material can have suitable hydrophilicity and strength, high fixation of cells after seeding, and highly efficient cell proliferation.

Scaffolding material for cell cultures and cell culture method using same

A scaffolding material for cell culture, which has a dispersion component γof the surface free energy of 24.5 mJ/mor more and less than 45.0 mJ/m, and a dipole component γof the surface free energy of 1.0 mJ/mor more and less than 20.0 mJ/m. According to the scaffolding material for cell culture, the scaffolding material can have suitable hydrophilicity and strength, high fixation of cells after seeding, and highly efficient cell proliferation.

A scaffolding material for culturing a stem cell, which contains a synthetic resin, and has a nitrogen content of the synthetic resin of 0.1% by mass or more and 10% by mass or less. According to the scaffolding material for stem cell culture, the scaffolding material can have suitable hydrophilicity and strength, high fixation of stem cells after seeding, and highly efficient cell proliferation.

Growing community of inventors

Osaka, Japan

Hiroki Iguchi