Nippon Kayaku Co., Ltd

Meiji Seika Pharma Co., Ltd.

Meiji Seika Kaisha, Ltd.

Hiroki Hotta

Kazumi Yamamoto

Shizuo Shimano

Nobuto Minowa

Nozomu Nakanishi

Akinori Morikawa

Hiroshi Kurihara

Takashi Watanabe

Ryo Horikoshi

Kazuhiko Oyama

Yasuhito Kato

Kenichi Yamamoto

Kouki Tanigakiuchi

Mikio Sekiguchi

Takaaki Miyake

Jun Iwabuchi

An objective of the present invention is to provide a process for producing 4-carbonyl oxyquinoline derivatives useful as agricultural and horticultural pesticides and fungicides. The objective can be attained by a process for producing 4-carbonyl oxyquinoline derivatives represented by general formula (1), the process including reacting a quinolone derivative with a halogenated compound or an acid anhydride in the presence of a phase transfer catalyst and a base. 

Process for producing 4-carbonyloxyquinoline derivatives

An objective of the present invention is to provide a crystal of 2-ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy)quinoline-4-yl methyl carbonate having stable physicochemical properties. The objective is attained by a crystal of 2-ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy)quinoline-4-yl methyl carbonate that exhibits a diffraction peak pattern shown in FIG.as determined by powder X-ray diffractometry.

Stabilized crystal of 2-ethyl-3,7-dimethyl-6-(4-(trifluoromethoxy)phenoxy)quinoline-4-yl methyl carbonate, process for producing the crystal, and agricultural chemical composition comprising the crystal

Disclosed is a process for producing 6-aryloxyquinoline derivatives useful as insecticides or fungicides for agricultural and horticultural use. The process comprises a cyclization reaction step of reacting an anthranilic acid derivative represented by general formula (1) with a kenone in the presence of an acid to obtain a quinolone derivative and a condensation reaction step of reacting the quinolone derivative with a halogen compound or an acid anhydride to obtain a quinoline derivative. 

Process for producing 6-aryloxyquinoline derivative and intermediate therefor

Disclosed are compounds that have excellent insecticidal activity and are usable as agricultural and horticultural insecticides. Compounds represented by formula (I) or agriculturally and horticulturally acceptable acid addition salts thereof have excellent insecticidal activity and are usable as agricultural and horticultural insecticides. 

Quinoline derivatives and insecticide comprising thereof as active ingredient

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Saitama, Japan

Hiroki Hotta