Olympus Optical Company, Ltd.

Olympus Corporation

Nippon Telegraph and Telephone Corporation

Isis Innovation Limited

Olympus Optical

Hiroki Hibino

Takashi Tsukaya

Sakae Takehana

Akira Suzuki

Masaaki Hayashi

Yoshinao Oaki

Takeaki Nakamura

Syuichi Takayama

Kenji Kimura

Shuichi Takayama

Koichi Matsui

Yutaka Takahashi

Hitoshi Mizuno

Yasuhiro Ueda

Kenji Yoshino

Masakazu Gotanda

Naoki Uchiyama

Hisao Yabe

Masahide Kanno

Akihiro Horii

Akira Taniguchi

Tetsumaru Kubota

Masao Uehara

Naomi Sekino

Tatsuya Yamaguchi

Tadao Hagino

Akira Hasegawa

Shinji Yamashita

Masahiko Sasaki

Akinobu Uchikubo

Akio Nakada

Tsutomu Yamamoto

Shinji Hatta

Katsuichi Imaizumi

Hideyuki Adachi

Koichi Shimizu

Mamoru Kaneko

Takefumi Uesugi

Isami Hirao

Toshihiko Hashiguchi

Toshimasa Kawai

Keiichi Hiyama

Koji Takamura

Yutaka Yanagawa

Katsunori Sakiyama

Hiroyuki Sasa

Takeshi Ozawa

Akira Murata

Toshiaki Nishikori

Atsushi Okawa

Shinichi Kato

Susumu Takahashi

Jun Hasegawa

Kimihiko Nishioka

Hiroshi Sasaki

Tatsuo Nagasaki

Hideo Ito

Hironobu Takizawa

Minoru Yamazaki

Takao Tsuruoka

Hiroyuki Fukuda

Katsuyuki Saito

Seiji Yamaguchi

Yoshio Tashiro

Yoshihiro Iida

Koji Yamaya

Osamu Tamada

Tomohisa Sakurai

Tetsuo Nonami

Hitoshi Karasawa

Masato Toda

Katsuaki Morita

Hideo Adachi

Takehiro Nakagawa

Shinichiro Hattori

Takao Rokutan

Hiromasa Suzuki

Toshiaki Noguchi

Kuniaki Kami

Nobuo Yamashita

Yuichi Yamada

Toshihiko Suzuta

Akira Matsueda

Yoshio Shishido

Yasuharu Hakamatsuka

Hideo Tomabechi

Akira Yokota

Shiro Bito

Michio Sato

Tatsuya Kubota

Masahiro Kudo

Yoshiharu Saito

Teruo Eino

Hisao Ogiu

Raifu Matsui

Fumiaki Ishii

Minoru Tsuruta

Masanao Murata

Kazunari Kobayashi

By widening a terrace on a crystal surface on a bottom face of a recess by step flow caused by heating, a flat face is formed on the bottom face of the recess, a two-dimensional material layer made of a two-dimensional material is formed on the formed flat face, and then a device made of the two-dimensional material layer is produced.

Two-dimensional material device and method for manufacturing same

A protein chip including at least a substrate having a plurality of steps which are regularly arranged on one surface thereof; a plurality of metallic microstructures arranged in the steps; and a lipid vesicle in which an outer surface thereof is modified by a functional group and a protein is present in a lipid bilayer thereof. The metallic microstructures and the lipid vesicle are bound via the functional group to provide the protein on the substrate.

Protein chip and production method thereof

A nerve stimulation apparatus performs nerve stimulation of a required level while reducing the adverse effect on the heart and on the detection of a cardiac event. Provided is a nerve stimulation apparatus that includes a stimulation signal output unit that outputs a nerve stimulation signal; a cardiac event detector that detects a cardiac event; and a controller that controls the stimulation signal output unit so as to output a nerve stimulation signal having a smaller intensity in a non-refractory period than that in a cardiac refractory period that is obtained on the basis of the cardiac event detected by the cardiac event detector.

Nerve stimulation apparatus

Provided is a nerve stimulation apparatus that is capable of performing effective nerve stimulation depending on a therapeutic purpose without adversely affecting a heart. Further provided is a nerve stimulation apparatus including: a stimulation-pulse output unit that outputs a stimulation pulse; a cardiac-event detector that detects a cardiac event; and a controller that controls the stimulation-signal output unit so as to output, during a cardiac refractory period, the nerve stimulation signal having an intensity that corresponds to the heart rate obtained on the basis of the cardiac event detected by the cardiac-event detector.

The present invention discloses a cell culturing system that cultures predetermined cells collected from a patient and supplies cultured cells to the original patient, which together with enabling correlations between the cultured cells and the supplier of the cells to be managed accurately and easily at all times, allows cultured cells and patients to be collated rapidly.

Cell culture system apparatus for checking cultured cells and apparatus for culturing cells

Contamination by dust particles, bacteria and so forth in each processing step can be reduced by a simple constitution. A culture vessel is used in which a medium vessel in which a medium is sealed and a waste medium vessel capable of housing the fluid in a main culture vessel are connected to the main culture vessel by connecting lines capable of restricting the flow of fluid between them in a state in which they are sealed from the outside. A culture apparatus is composed in which the inner volume of each vessel is variable, and is provided with a case provided with indentations for housing each vessel, and a pressing means that contracts the vessels housed in the indentations by applying external pressure.

Incubator and culture device

An identification circuit () recognizes optical probes (A,B) of different scanning types that are connected to a light source unit () and a control device (), the frequency of the drive signal of a control circuit () for driving a scanner inside the optical probe is varied by this recognition signal, corresponding drive signals are applied to the optical probes connected, the scanner of each probe is scanned, and two-dimensional optical information is imaged by an imaging device () and displayed on a monitor ().

Optical scanning probe system

A light scanning device has a tip structure which includes a light scanning part connected to a light source, and which is insertable into a body cavity and is formed so as to be water-tight. A controlling part controls the light scan through the tip structure, and the tip structure and the controlling part are also connected to each other in a water-tight manner by a slender tube through which a plurality of electrical cables pass. An electric connector is fixed with the proximal end portion of the tube in a water-tight manner, and is electrically connectable so as to be water-tight with and removable from this controlling part.

Light scanning devices of a water-tight structure to be inserted into a body cavity to obtain optical information on inside of a biological tissue

A low coherence beam emitted by a low coherence light source is split into two portions. One portion is transmitted from the outward end of a first single mode fiber via a detachable connector to a beam scanning probe, and then to a biological tissue; and the other is transmitted from an optical coupler placed midway along the light path via a second single mode fiber to a light path modifier. The light path modifier includes a galvanometer mirror to modify the light path length in accordance with a scan range, and a uniaxial stage to adjust the light path length to absorb the variation in lengths of different beam scanning probes. The light path is adjusted by the uniaxial stage such that the beam interference is detected for the scan range, to ensure stable acquisition of tomographic images.

Optical imaging apparatus which radiates a low coherence light beam onto

An endoscope system having an endoscope, a scope holder holding the endoscope, a magnetic three-dimensional position sensor, and a TV monitor. The sensor detects the position of an object and generates data representing this position. According to the data, the view field of the endoscope is switched.

Image tracking endoscope system

In an endoscope system including an endoscope having an insertion section to be inserted into a cavity under inspection, a bending portion which is provided in the insertion section near a distal end thereof and is bent in at least up and down directions and an operation section to which a proximal end of the insertion section is connected and a disposable protection cover having an insertion section dover for covering the insertion section of the endoscope and having formed therein an insertion section inserting channel into which the insertion section of the endoscope is insertable and conduit channels, the insertion section inserting channel and conduit channels are both crossed by a line which is parallel with the up and down directions, so that the distal end of the insertion section can be correctly bent in the up and down directions without being influenced by the conduit channels.

Endoscope system including endoscope and disposable protection cover

A curvature section provided in an insertable section is curved in response to a curving instructing signal output by the operation of a curving operating switch. In case the curving operating switch is of a joy stick type having an operating lever, in response to the operation of a switching switch, a mode in which the inclination angle of the operating lever is held and a mode in which the inclination angle of the operating lever is returned to a neutral position in which it is zero will be switched and the curvature section will be of a curvature angle following the inclination angle of the operating lever. In case the curving operating switch is of a joy pad type comprising a plurality of on/off switches, in response to the operation of the switching switch, the curvature instructing signal will be held or reset.

Endoscope apparatus capable of being switched to a mode in which a

In an endoscope, a curvature indicating element for curvature-indicating a curvable curvature section provided adjacent to a distal end of an elongated inserting section having elasticity is arranged at a location close to a thumb of a hand grasped by an operator in the operating section provided at a proximal end portion of an inserting section. An operating element for controlling operation of fluid such as outflow, inflow or the like is arranged at location opposite to the curvature indicating element in the operating section. Thus, operations of the curvature operation, outflow and inflow of the fluid and the like can be executed simultaneously under a condition where the operating section is grasped.

Endoscope apparatus provided with curvature and fluid flow control

An endoscope apparatus according to the present invention includes a warping velocity control device which receives an angle of warp detected by an angle detection device and a value of an electric current realized at this angle of warp and detected by an electric current detection device. The control device makes comparisons between the angle of warp and the value of the electric current and data about a normal state stored in a storage device. If the result is larger than data for the normal state by a predetermined value, the warping velocity is lowered while a discrimination is made that an abnormal state (the warp-enabled portion has come in contact with the body wall) takes place. Additionally, the apparatus could include a time detecting device for detecting a time in which an electric quantity supplied to a drive means is larger than a predetermined time. The warping velocity control device controls the warping velocity according to the comparison made by the time detecting device.

Electromotive warping type endoscope with velocity control

Disclosed herein is a surgical device for applying surgical fasteners to body tissues in order to fasten the body tissues together. The device comprises an operation section having a housing having an inner space completely sealed from the outside, drive elements electrically driven and arranged in the inner space of the operation section, an insertion section including a housing which has a first end portion containing the fasteners and having an opening through which the fasteners are to be applied, and a second end portion removably coupled to the housing of the operation section, fastener-applying elements located in the housing of the insertion section, for applying the fasteners from the opening to body tissues, and force-transmitting elements for transmitting drive force from the drive elements to the fastener-applying elements.

Surgical device for stapling and fastening body tissues

Growing community of inventors

Hachioji, Japan

Hiroki Hibino