Daiichi Pure Chemicals Co., Ltd.

Toudai Tlo, Ltd.

Sekisui Medical Co., Ltd.

Hirokazu Yago

Osamu Miyazaki

Hiroyuki Ebinuma

Takashi Kadowaki

Toshimasa Yamauchi

Yuka Akimoto

Kazuo Hara

Yoshiro Niitsu

Koji Ushizawa

Kazunori Saito

Kazuo Kotani

Junji Kato

Chizuru Morikawa

Masanao Matsuo

Remi Ikeda

Remi Nakamura

Hisashi Hanada

Yutaka Kohgo

Mari Emmi

Hiroyuki Sunaga

Yuki Honjo

Osamu Myazaki

To provide a method for stabilizing unstable &#x3b1;-thrombin in a thrombin-containing solution, a solution containing stabilized &#x3b1;-thrombin, and a liquid fibrinogen assay reagent containing the solution. The method for stabilizing &#x3b1;-thrombin in a thrombin-containing solution, which includes adjusting the percentage of &#x3b1;-thrombin to 70% or more with respect to the amount of total thrombin in the thrombin-containing solution.

Method for stabilizing &#x3b1;-thrombin in thrombin-containing solution

Kits and methods for selectively assaying a target adiponectin multimer in a biological sample. Such methods accurately evaluate the relationship between a disease and adiponectin through selective assay of adiponectin multimers and provide information that cannot be obtained through measurement of the total amount of adiponectin alone. A method for selectively assaying a target adiponectin multimer in a biological sample comprising distinguishing target adiponectin multimer from the other adiponectin multimers by using a protease and/or an antibody.

Method of selectively assaying adiponectin multimers

The invention provides a method of pretreating a sample for conveniently, quickly and accurately measuring the total amount of adiponectin present in a biological sample contaminated with various adiponectin multimers. The method of measuring an sample for immunologically assaying the total amount of adiponectin present in the sample comprises reacting, with an adiponectin-containing sample, at least one of a reducing agent, an acid or a salt thereof, a surfactant, and a protease.

Mehod of pretreating sample and immunological assay method using the same

Methods for selectively assaying a target adiponectin multimer in a biological sample. Such methods accurately evaluate the relationship between a disease and adiponectin through selective assay of adiponectin multimers and provide information that cannot be obtained through measurement of the total amount of adiponectin alone. A method for selectively assaying of a target adiponectin multimer in a biological sample comprising distinguishing target adiponectin multimer from the other adiponectin multimers by using a protease and/or an antibody.

Stable plasmin solution

Method of assaying asialoglycoprotein receptor and assay reagent therefor

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Ryugasaki, Japan

Hirokazu Yago