Environmental Research Institute

Hirokazu Okudaira

Akio Mori

A method of inhibiting human IL-5 gene transcriptions mRNA expression and protein production by human T-cells using one or more compounds selected from those shown by formula I shown below (where R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently a C.sub.1 -C.sub.6 alkyl group) and a therapeutic agent for allergic and eosinophilic inflammatory diseases which contains one or more compounds selected from those shown by the formula. ##STR1##

Drugs for allergic and eosinophilic diseases

A method of inhibiting human IL-5 gene transcription, mRNA expression and protein production by human T-cells using one or more compounds selected from those shown by formula I shown below (where R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are each independently a C.sub.1 -C.sub.6 alkyl group) and a therapeutic agent for allergic and eosinophilic inflammatory diseases which contains one or more compounds selected from those shown by the formula. ##STR1##

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Tokyo, Japan

Hirokazu Okudaira