Hitachi, Ltd.

Hirokazu Kato

Kenji Yasuda

Kazunori Okano

Jun Otomo

Tomoko Takeshita

Noboru Moriya

Shokichi Matsunami

Sakae Saito

Sayuri Nomura

Different probes each having a specific base sequence are immobilized to each of independent areas formed on the surface of a substrate, complementary polynucleotides in a sample solution are hybridized to the probes, and each of the independent areas on the substrate is heated and then cooled in sequence, and hence the solution is recovered to extract different polynucleotides separately corresponding to individual probes.

Polynucleotide separation method and apparatus therefor

An automatic electrophysiological measuring apparatus to automatically penetrate a glass electrode(s) into the membrane of a Xenopus Oocyte to hold the membrane potential and to automatically measure reactions to the administration of a medicine is to be provided. A glass electrode in the air is moved toward a Xenopus Oocyte held in a cell. Changes in the potential states of the glass electrodes are picked up by a control computer to distinguish the relative positions of the glass electrode and the Xenopus Oocyte , and the sequence of electrophysiological measurement so as to penetrate the glass electrode into the Xenopus Oocyte , hold the membrane potential and automatically administer the medicine.

Automatic electrophysiological measuring apparatus/method

Automatic electrophysiological measuring apparatus / method

Cell component recovery method

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Hiki-gun, Japan

Hirokazu Kato