Yamanouchi Pharmaceutical Company Ltd.

Hiroitsu Kawada

Masuo Murakami

Tadayoshi Ohmura

Jun Sekino

Hidemi Shimizu

Kiyoshi Okazaki

Kenichi Tomioka

Hiroshi Sugiura

Shigemi Kawahara

Hidefumi Matsui

Hiroo Maeno

A pharmaceutical composition for rectal administration containing 11.alpha.,15(S)-dihydroxy-20-methoxy-16(S)-methyl-9-oxo-5(cis,13(trans)-pr ostadienoic acid or a water-soluble salt thereof dissolved or dispersed in a lipophilic or hydrophilic base in the presence or absence of a buffer solution or an aqueous organic amine solution.

Pharmaceutical compositions of a prostaglandin compound for rectal use

There is disclosed a dry, stabilized oral pharmaceutical formulation containing a prostaglandin E group prepared from a lyophilized composition comprising a prostaglandin E group and at least a member selected from the group consisting of a thiol compound, dextrin, dextran, a lower alkyl cellulose, and a water-soluble salt of deoxycholic acid.

Stabilized oral prostaglandin formulation and the process for the

A dried and stabilized prostaglandin composition containing a prostaglandin E group compound with calcium lactate and/or amylopectin, and a stabilized pharmaceutical preparation for practical administration prepared from the said composition.

Stabilized prostaglandin composition and the process for the preparation

A single phase solid composition wherein one part of a non-aqueous liquid and 0.5-6 parts of calcium lactate hydrate are mixed and heated. The product according to this invention is very stable and can be formed into various kinds of moldings by a simple operation so that it may be applied to many uses.

Solid composition

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Tokyo, Japan

Hiroitsu Kawada