Mitsubishi Chemical Industries Limited

Nippon Shinyaku Company, Ltd.

Hiroaki Munakata

Hiroshi Enomoto

Makio Kobayashi

Kazuo Wagatsuma

Makoto Tsurufuji

Shigeru Sato

Makoto Sugiyama

Iwao Morita

Yoshihisa Shibata

Shingo Matsumura, Deceased

Tomio Inokuchi

Seiu Iida

Phenylacetic acid derivatives of the formula: ##STR1## wherein R.sup.1 is hydrogen or ##STR2## wherein R.sup.5 is an alkyl group of 1-6 carbon atoms or an aryl group; R.sup.2 and R.sup.3 are independently hydrogen or an alkyl group of 1-4 carbon atoms; R.sup.4 is hydrogen or an alkyl group of 1-4 carbon atoms, have been found to possess immunomodulating activity.

Immunomodulating agent

There are disclosed an acylated derivative of water extract of Anemarrhenae rhizoma which is so-called 'Chimo', and a hypoglycemic agent containing the above acylated derivative of water extract of Chimo as an active ingredient.

Hypoglycemic agents

Glutamine derivatives and non-toxic salts thereof have been found to have immunomodulating activities.

Glutamine derivatives

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Sagamihara, Japan

Hiroaki Munakata