Canon Medical Systems Corporation

Hiroaki Kushima

Tetsuya Kuwabara

Jun Okada

Hirotaka Unno

Sotaro Taki

Masayuki Yumoto

Nobuo Kawamura

Kenichi Arame

In a nucleic acid detection cassette, a predetermined syringe is crushed to supply a sample solution to an amplification unit via a channel and the amplification unit is heated from outside to amplify sample DNA in the sample solution. The sample solution containing an amplification product is supplied to a detection unit via the channel and a hybridization reaction occurs in the detection unit. Next, another syringe is crushed and an intercalating agent solution is supplied via another predetermined channel. Therefore, a nucleic acid detection cassette capable of automation from amplification of a sample to detection of an electrochemical reaction of the sample is provided.

Nucleic acid detection cassette

According to one embodiment, a sealed chemical container has a bonding area where a flexible sheet-like member is firmly bonded onto a plate, and the bonding area defines a first compartment which can be swollen and an outflow passage which communicates with the first compartment via an opening. A first seal portion is weakly bonded onto the plate compared to the bonding area to define the first compartment to block communication between the first compartment and an outflow passage. The first seal portion is peeled off by an increase in internal pressure in the first compartment to allow communication between the first compartment and the outflow passage.

Chemical container

Growing community of inventors

Fujisawa, Japan

Hiroaki Kushima