Toyobo Co., Ltd.

Hiroaki Kitazawa

Takahide Kishimoto

Yoshihisa Kasukabe

Shusaku Yanagidani

Yosuke Sumida

Hiroshi Aiba

Yuu Utashima

Rie Hirao

Masaru Kitagawa

Chiaki Yamada

The invention provides streptolysin O containing a polypeptide comprising an amino acid sequence having deletion of a polypeptide extending from a lysine residue at position 2 of SEQ ID NO: 1 to any of an alanine residue at position 31, a glutamate residue at position 32, a serine residue at position 33, and an asparagine residue at position 34, and also having deletion of any of an isoleucine residue at position 465 to an alanine residue at position 472 of SEQ ID NO: 1 and all of the subsequent amino acid residues, as well as variants thereof and related DNA, vectors, transformants, and methods of use thereof.

Modified streptolysin O

The present invention provides a novel glucose dehydrogenase that has excellent substrate specificity, specific activity, thermal stability, and the like, and that is suitable for use in SMBG sensors. The present invention provides a purified polypeptide comprising an amino acid sequence having at least 80% identity to the sequence of SEQ ID NO: 1 and having glucose dehydrogenase activity.

Glucose dehydrogenase

A method for producing a polyamine composition with high production efficiency that has a low salt concentration includes (1) a step of treating a plant and/or a processed plant product with ethanol; (2) a step of treating the plant and/or the processed plant product with water; (3) a step of treating the plant and/or the processed plant product under an acidic condition; and (4) a step of separating and collecting a liquid fraction.

Method for producing polyamine composition from plant

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Tsuruga, Japan

Hiroaki Kitazawa