Arthrocare Corporation

Vytronus, Inc.

Aneumed, Inc.

Auris Health, Inc.

Arthocare Corporation

Advanced Angioplasty Products, Inc.

Thapliyal and Eggers Partners

Other

Advanced Surgical, Inc.

David a. Gallup

Hira V. Thapliyal

James W. Arenson

Hira V Thapliyal

Philip E Eggers

David C Hovda

Jean Woloszko

David A Gallup

James W Arenson

Maria B Ellsberry

Ronald A Underwood

Terry S Davison

Phillip M Olsen

Michael A Baker

Stephen M Brunell

Robert Brommer

Lewis Sharps

Andrew R Eggers

Tim Proulx

Allan Weinstein

John P Mohr, Iii

Paul O Davison

James L Pacek

James P Tasto

Olivier Ricart

Katherine M Williams

Andrew M L Cheng

Paul W Mohr

Craig Tsuji

Neville Alleyne

Malcolm D Heaven

Christopher Lee Willink

Philip Eugene Eggers

Michael W Jopling

Andrew M Cheng

Philip M Olsen

Jimmy V Ngo

Robert A Brommer

Paul Mohr

Philip E Eggers & Associates Inc Eggers

A system for ablating target tissue includes an elongate anchor shaft, a radially expandable member coupled to the elongate anchor shaft, and an elongate ablation shaft. The radially expandable member has an expanded configuration for engagement with the target tissue to facilitate anchoring. The elongate ablation shaft may be slidably disposed in the elongate anchor shaft, and the distal portion of the elongate ablation shaft is steerable. An energy source is coupled to the elongate ablation shaft and is configured to deliver energy to the target tissue and ablate the target tissue. Actuation of the elongate ablation shaft directs the energy to the target tissue to form a desired ablation path in the target tissue.

Steerable ablation catheter

Systems and methods for ablating tissue include an ablation device having an energy source and a sensor. The energy source provides a beam of energy directable to target tissue, and the sensor senses energy reflected back from the target tissue. The sensor collects various information from the target tissue in order to facilitate adjustment of ablation operating parameters, such as changing power or position of the energy beam. Gap distance between the energy source and target tissue, energy beam incident angle, tissue motion, tissue type, lesion depth, etc. are examples of some of the information that may be collected during the ablation process and used to help control ablation of the tissue.

System and method for energy delivery to tissue while monitoring position, lesion depth, and wall motion

An ablation system for treating atrial fibrillation in a patient comprises an elongate shaft having proximal and distal ends, a lumen therebetween and a housing adjacent the distal end of the elongate shaft. An energy source is coupled to the housing and is adapted to deliver energy to a target tissue so as to create a zone of ablation in the target tissue that blocks abnormal electrical activity thereby reducing or eliminating the atrial fibrillation in the patient. A sensor is adjacent the energy source and adapted to detect relative position of the energy source to the target tissue or characteristics of the target tissue. The system also has a reflecting element operably coupled with the energy source and adapted to redirect energy emitted from the energy source in a desired direction or pattern.

System and method for delivering energy to tissue

A cardiac ablation method including the following steps: inserting a treatment catheter into an atrium of a heart, the treatment catheter including an ultrasound emitter; positioning the ultrasound emitter to face heart tissue within the left atrium outside of a pulmonary vein; emitting ultrasound energy from the ultrasound emitter while rotating the ultrasound emitter about a rotation axis; and ablating heart tissue with the ultrasound energy to form a lesion outside of a pulmonary vein.

Method for ablating body tissue

Methods for ablating tissue in a patient having atrial fibrillation comprise advancing an elongate flexible shaft through a patient's vasculature into a chamber of a heart. The elongate flexible shaft has an energy source and a sensor. Tissue in the heart is scanned with the sensor and data about the tissue is captured. The captured data is grouped into one of a plurality of tissue classifications and an anatomical map of the tissue showing the grouped data is displayed. At least a portion of the tissue is ablated so as to form a conduction block that blocks aberrant electrical pathways in the heart. The ablated tissue is grouped into one or more predefined tissue classifications during or prior to the ablation.

System and method for anatomical mapping of tissue and planning ablation paths therein

A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration engages the personalized prosthesis with the treatment site. The mesh or membrane is personalized to match the treatment site in the expanded configuration, and has an outer surface that substantially matches the treatment site shape and size. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.

Personalized prosthesis and methods of use

A personalized prosthesis for implantation at a treatment site of a patient includes a self-expanding mesh and/or membrane having collapsed and expanded configurations. The collapsed configuration is adapted to be delivered to the treatment site, and the expanded configuration is oversized relative to the treatment site and configured to engage the personalized prosthesis with the treatment site. The self-expanding mesh is configured to reduce in one or more dimensions in response to being constrained in the one or more dimensions, such that the mesh in the expanded configuration self-adjusts to the treatment site without buckling of the mesh. The self-expanding mesh or membrane forms a central lumen configured to allow blood or other body fluids to flow therethrough. Methods of manufacturing and delivery of the personalized prosthesis are also disclosed.

Personalized prosthesis and methods of deployment

An ablation system for treating atrial fibrillation in a patient including an elongate shaft having proximal and distal ends, a lumen therebetween and a housing adjacent the distal end of the elongate shaft. An energy source is coupled to the housing and is adapted to deliver energy to a target tissue so as to create a zone of ablation in the target tissue that blocks abnormal electrical activity thereby reducing or eliminating the atrial fibrillation in the patient. A sensor is adjacent the energy source and adapted to detect relative position of the energy source to the target tissue or characteristics of the target tissue. The system also has a reflecting element operably coupled with the energy source and adapted to redirect energy emitted from the energy source in a desired direction or pattern.

A personalized prosthetic valve for implantation at a native valve treatment site includes a self-expanding mesh and a plurality of valve leaflets coupled to the mesh. The mesh may be delivered to the native valve in a collapsed configuration, and in an expanded configuration the mesh engages the native valve. The mesh in the expanded configuration is also personalized to match the treatment site, such that the outer mesh surface substantially matches the treatment site shape and size. The self-expanding mesh forms a central lumen configured to allow blood or other body fluids to pass therethrough. In the open configuration, blood passes through the prosthetic valve, and in the closed configuration, the plurality of leaflets are closer together and blood is prevented from flowing upstream through the prosthetic valve.

Personalized aortic valve prosthesis

A method for creating a transmural lesion in tissue includes positioning a distal portion of a catheter near the tissue, where an ultrasound transducer is attached to the distal portion and is operatively coupled to a console and processor. The tissue is imaged by energizing the ultrasound transducer at a first power level to produce an ultrasound beam, where the imaging determines a thickness of the tissue, and a gap distance between the ultrasound transducer and the tissue. The tissue is ablated by energizing the ultrasound transducer at a second power level to produce the ultrasound beam. Energy delivered to the tissue during the ablating is controlled, using the processor, where the processor adjusts a speed of the ultrasound beam moving across the tissue based on the thickness and gap distance, to create the transmural lesion.

Methods for imaging and ablating body tissue

A tissue ablation method for treating atrial fibrillation in a patient comprises locating an ostium of a pulmonary vein and positioning an interventional catheter adjacent the ostium. The interventional catheter has an energy source. Collateral tissue adjacent the ostium is located and tissue around the ostium is ablated with energy from the energy source so as to form a contiguous lesion circumscribing the ostium. The lesion blocks aberrant electrical pathways in the tissue so as to reduce or eliminate the atrial fibrillation. The ablating is modified so as to avoid ablating or otherwise damaging the collateral tissue.

System and method for ultrasound ablation of tissue while compensating for collateral tissue

Growing community of inventors

Los Altos, CA, United States of America

Hira V Thapliyal