Other

Bvw Holding Ag

Polymaterials Ag

Schieker, Matthias

Hinrich Wiese

Michael Milbocker

Lukas Bluecher

Gerhard Maier

Uta Moll

Joerg Tessmar

Matthias Schieker

Martina Kessler

The present disclosure provides copolymers useful in medical devices. For example, the disclosure provides copolymers comprising the polymerization product ester block, ether blocks and diisocyanates. In certain embodiments, the disclosure provides a medical copolymer for implantation comprising ester blocks and ether blocks, wherein: the ester blocks comprise a negative free energy transfer and the ether blocks comprise a positive free energy transfer, the ether and ester blocks are less than 1/10 the length of said copolymer, and, the blocks are distributed such that no domain of contiguous blocks possessing the same polarity of free energy transfer are less than &#x2153; of the molecular weight of the copolymer. The disclosure further provides methods of making the aforementioned polymers, and medical devices comprising the polymers.

Surgical barriers possessing clinically important absorption characteristics

According to the invention, thermoreversible hydrogels are provided, which are prepared from chain-extended poloxamers, having advantageous properties. In addition, the invention provides thermoreversible hydrogels, including biological materials, and a process for the preparation thereof, thermoreversible hydrogels including living cells, application systems for pharmaceutical applications, and an in-vitro-method for forming a composition on a surface.

Chain-extending poloxamers, thermoreversible hydrogels formed by them which include biological materials, and medicinal applications of same

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Unna, Germany

Hinrich Wiese