Avinger, Inc.

Endotex Interventional Systems, Inc.

Covidien LP

Fox Hollow Technologies, Inc.

Boston Scientific Scimed, Inc.

Other

Tyco Healthcare Group LP

Boston Scientific Cupertino Corporation

Ethicon, Gmbh

Endotek Interventional Systems, Inc.

Medtronic Minimed, Inc.

Narang, Ajit S.

Himanshu N Patel

Sheldon B Moberg

John B Simpson

Farhad Khosravi

Michael H Rosenthal

Michael Zung

Charles W McNall

Maegan K Spencer

Anthony J Fernandez

John C Spiridigliozzi

Priyanshu Gupta

Richard Roy Newhauser, Jr

John F Black

Manish Kankaria

Dennis W Jackson

Christopher B White

Gautama B Venegas

Greg Stine

Michael Hogendijk

Brett Allen Follmer

Kin F Chan

Vincent Yeh

Michael Peter Ross

Mehrdad Farhangnia

Ryan Radjabi

Wendy Ngo Lam

Yi Yang

Theodore W Ketai

Nicholas J Spinelli

Mike Rosenthal

Charles W Mcnall

Robert J Tannhauser

Kent C B Stalker

Darren G Doud

Peter H Smith

Stephen Charles Davies

Michael R Ross

Bradley J Enegren

Emilian Istoc

Mark West Askew

Kaezad J Mehta

Eduardo U Sucgang

Myra L Fabro

Christina Van

Glenn O Spital

Bogdan Madzar

Richard L Dalrymple, Jr

Martin T Zdanowicz

Daniel Leong

Farhangnia Mehrdad

Noel Nhu-Ngoc Nguyen

Anupama Karwa

Kent Cb Stalker

Richard K Yoon

John J Mika Iii

James Jollota

Charles Tolle

An atherectomy catheter includes an elongate catheter body, a cutter at a distal end of the catheter body, and a nosecone attached to a distal end of the catheter body. The cutter is configured to excise tissue from the body. The nosecone is configured to hold tissue excised from the cutter. The nosecone includes a distal section, a proximal section, and a connection mechanism that is configured to allow the distal section to attach and detach from the proximal section during use. The distal section includes a plug configured to sit within an inner diameter of the proximal section when the proximal section is connected to the distal section.

Catheter device with detachable distal end

A catheter device for crossing occlusions includes an elongate body, a central lumen extending within the elongate body from the proximal end to the distal end, a rotatable tip at the distal end of the elongate body, and an OCT imaging sensor. The rotatable tip is configured to rotate relative to the elongate body. The OCT imaging sensor includes an optical fiber coupled with the rotatable tip and configured to rotate therewith. A distal end of the elongate body includes one or more markers configured to occlude the OCT imaging sensor as it rotates. A fixed jog in the elongate body proximal to the distal end of the catheter positions the distal end of the catheter at an angle relative to the region of the catheter proximal to the fixed jog and is aligned with the one or more markers on the elongate body.

Occlusion-crossing devices, imaging, and atherectomy devices

Occlusion crossing devices and systems. An inner shaft may be configured to rotate and extend within an outer shaft. The inner and outer shafts may include engagement regions to limit distal movement of the inner shaft within the outer shaft. The outer shaft may include a distal opening that is angled to form a tapered distal end. The inner shaft may include a distal end having a fluted tip with cutting edges that are configured to extend through the distal opening of the outer shaft. The inner shaft may include an imaging window. When the cutting edges are fully extended distally through the distal opening of the outer shaft, the tapered distal end of the outer shaft may be configured to occlude the imaging window at a defined rotational position as the inner shaft is rotated relative to the outer shaft to provide a registration mark for imaging.

Occlusion-crossing devices

An atherectomy catheter for use in a vessel includes a catheter body, a nosecone and an annular cutter. The catheter body has a curved portion with a fixed jog section and an adjacent flexible section having a greater flexibility than a remainder of the catheter body. The fixed jog section and the flexible section include a frame having circumferential slits arranged in rows and in a circumferentially offset pattern. The circumferential slits of the flexible section are configured to allow the flexible section to passively bend in multiple directions during positioning of the catheter body within the vessel. The fixed jog section further includes a longitudinal spline having a pre-set curvature. The nosecone is attached to a distal end of the catheter body and includes a cutting window. The annular cutter configured to rotate with respect to the catheter body and positioned within the cutting window.

Atherectomy catheter with shaped distal tip

A catheter for positioning a guidewire across an occluded portion of a vessel includes an elongate catheter body, an integrated rotatable distal tip, a proximal handle region, and a catheter lumen extending through the elongate catheter body. The elongate body has a distal region configured to be bent to a set angle. The integrated rotatable distal tip includes one or more channeled flutes extending around the distal tip that are configured to be rotated in a first direction to dissect tissue and a second direction for bluntly contacting tissue. A proximal handle region includes a control for rotating the distal tip in either the first or second directions. The catheter lumen is configured to pass a guidewire.

Guidewire positioning catheter

A catheter system for optical coherence tomography includes an elongate catheter body, an optical fiber in the elongate catheter body, and an anamorphic lens assembly coupled with a distal end of the optical fiber. The optical fiber and the lens assembly are together configured to provide a common path for optical radiation reflected from a target and from a reference interface between the distal end of the optical fiber and the lens assembly.

Micro-molded anamorphic reflector lens for image guided therapeutic/diagnostic catheters

An atherectomy catheter device includes an elongate body, a drive shaft extending proximally to distally within the elongate body, and a cutter attached to the drive shaft. The cutter includes a serrated annular cutting edge formed on a distal edge of the cutter and a recessed bowl extending radially inwards from the annular cutting edge to a center of the cutter. The recessed bowl has a first curvature. The cutter further includes a plurality of grinding segments extending inwardly from the distal edge within the bowl. Each of the plurality of segments has a second curvature that is different from the first curvature.

Atherectomy catheter with serrated cutter

An occlusion crossing device includes an outer shaft, an inner shaft, an optical fiber, and a handle attached to the inner shaft and the outer shaft. The inner shaft extends within the outer shaft. The inner shaft includes a drill tip at a distal end thereof. The optical fiber extends within the inner shaft substantially along a central axis of the inner shaft. The distal tip of the optical fiber is attached to the drill tip. The handle is configured to rotate the inner shaft and drill tip at speeds of greater than 500 rpm.

High speed chronic total occlusion crossing devices

A catheter system includes a catheter that includes an outer shaft and a rotatable inner shaft having a drill tip. The catheter can be configured to bend laterally when the inner shaft is rotating within the other shaft for maneuvering within a blood vessel, for example, as the drill tip crosses an occlusion. Catheter bending can be activated by translating the inner shaft relative to the outer shaft in a distal direction, proximal direction, or both. The outer shaft may include a locking feature to rotatably lock the inner shaft with the outer shaft and allowing bidirectional lateral bending of the catheter. The inner shaft can include one or more imaging sensors for collecting images outside of the catheter. The inner shaft may be removable from the outer shaft, for example after an occlusion is crossed, to allow insertion of a guidewire or other device within the outer shaft.

An atherectomy catheter includes an elongate flexible catheter body, an elongate deflectable distal tip coupled to the catheter body at a hinge point, a rotatable cutter near the distal end of the catheter body, and a drive shaft extending within the catheter body and configured to rotate the cutter. The atherectomy catheter further includes an optical fiber extending through the drive shaft substantially on-axis with the catheter body and attached to the cutter. The optical fiber is configured to rotate with the drive shaft. The atherectomy catheter further includes a wedge configured to deflect the distal tip away from the catheter body at the hinge point upon axial movement of the drive shaft.

Atherectomy catheters with imaging

Described herein are atherectomy catheters, systems and methods that include longitudinally displaceable drive shafts that drive actuation of one or more cutters at the distal end of the catheter. The catheters described herein may include one or more imaging sensors for imaging before, during or after cutting tissue. In some variations the imaging sensor may be rotated around the perimeter of the catheter independently of the rotation of the cutter. Also describe herein are imaging catheters that may be used without cutters.

Atherectomy catheter

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San Jose, CA, United States of America

Himanshu N Patel