Covidien LP

Mayo Foundation for Medical Education and Research

Hillary K Huszar

Mark A Maguire

David S Utley

Shawn C Daniel

John O McWeeney

Allen Jameson

Christopher L Bagley

Gilbert Mata, Jr

Eric J Gwerder

Felicia P Sein-Lwin

Robert C Haggerty

Alexander Arthur Lubinski

Madeline A Mannion

Olivia P Metcalf

Thomas Pham

Allen D Jameson

Pratika Sah

Brian Tinkham

Elizabeth Rajan

Gilbert Mata

Akira Dobashi

David J Karasek

Ryan Bertwell

William Camisa

Ellie K Ahlquist

Scott Bartfield

David H Hamilton

Jr Mata Gilbert

Alexander A Lubinski

Jr Gilbert Mata

Gilbert Mata Jr

Mehdi Ebrahimian

Randall D Sullivan

Felicia P Seinlwin

Scott F Chang

A surgical system for performing an endoscopic submucosal dissection includes first and second surgical clips each having first and second jaw members for grasping tissue therebetween. The first surgical clip includes a resilient member attached to one of the jaw members and configured to bow outwardly to engage tissue. The jaw members of the first surgical clip each has a pointed tip and each of the jaw members of the second surgical clip has a blunt distal tip.

Systems for endoscopic submucosal dissection

Methods, apparatuses and systems are described for stent delivery and positioning to cover an access site. A stent delivery system may include a tubular member configured to advance through an access site and a primary constrainment member configured to releasably couple the stent to the tubular member. The stent delivery system may further include a secondary constrainment member at least partially disposed around the primary constrainment member, the stent, and the tubular member. In some cases, the tubular member and the primary constrainment member may be configured to reposition the stent within the body lumen after removal of the secondary constrainment member such that at least a portion of the stent covers the access site after withdrawal of the tubular member, the primary constrainment member, and the secondary constrainment member from the body lumen through the access site.

Apparatuses for stent delivery and positioning to cover an access site

Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering the stent through an access site and deploying a distal portion of the stent from within an outer sheath. In some cases, the method may further include pushing a proximal portion of the stent from the outer sheath such that upon fully exiting the outer sheath, the proximal portion extends proximally to at least partially cover the access site with the stent. The system for delivering the stent into the body lumen may include a stent, a stent delivery apparatus, and an outer sheath. The system may further include an internal pusher configured to push a proximal portion of the stent from the outer sheath and axially compress the stent such that upon fully exiting the outer sheath, the proximal portion extends proximally to cover the access site.

Expandable stent delivery apparatus to cover an access site

Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering a stent delivery system through an access site, where the stent delivery system comprises a positioning member with a first portion that is rotatable with respect to a second portion, and where the stent is releasably coupled with the first portion of the positioning member. In some cases, the method may further include withdrawing an outer constrainment member front the stent to deploy a proximal portion of the stent within the body lumen and rotating the proximal portion of the stent away from the access site by withdrawing the positioning member proximally and back through the access site. The method may further include covering the access site with the proximal portion of the stent upon fully deploying the proximal portion from the outer constrainment member.

Rotatable stent delivery apparatus to cover access site

An endoscopic surgical instrument deploys a hemostatic clip during endoscopic submucosal resection. The hemostatic clip has an elongated collar configured to be detachably coupled to a shaft of the surgical instrument, a pair of jaws received in the collar, and a magnet coupled to the jaws.

Systems and methods for endoscopic submucosal dissection using magnetically attachable clips

Methods, apparatuses and systems are described for stent delivery and positioning to cover an access site. The method may include delivering the stent through an access site in a wall of the body lumen. In some cases, the method may include repositioning the stent within the body lumen to at least partially cover the access site with the stent. The stent may be repositioned within the body lumen by retracting the stent towards the access site such that a proximal portion of the stent at least partially covers the access site. The stent may then expand within the body lumen. In some cases, the stent may expand within the body lumen by releasing a primary constrainment member from the stent by pulling the primary constrainment member in a proximal direction away from the stent.

Methods for stent delivery and positioning to cover an access site

Methods, apparatuses and systems are described for delivering a stent through an access hole of a body lumen and covering up the access hole after deploying the stent, Stents are described that include a stent body defining a body lumen contact surface area and a deployable member configured to deploy from the stent body and increase the body lumen contact surface area of the stent. Deployable members that hinge, unroll, extend, expand, and coaxially translate with respect to the stent body are described. A system for delivering a stent into a body lumen are described that may include a coverage member configured to at least partially cover the hole in the wall of the stent upon withdrawing a tubular member through the hole in the wall of the stent. Coverage members may include a self-sealing membrane, a flap valve, or a hinged valve.

Stent designs to cover catheter access site

Methods, apparatuses and systems are described for expandable stent delivery apparatus to cover an access site. The method may include delivering a stent delivery system through an access site, where the stent delivery system comprises a positioning member with a first portion that is rotatable with respect to a second portion, and where the stent is releasably coupled with the first portion of the positioning member. In some cases, the method may further include withdrawing an outer constrainment member from the stent to deploy a proximal portion of the stent within the body lumen and rotating the proximal portion of the stent away from the access site by withdrawing the positioning member proximally and back through the access site. The method may further include covering the access site with the proximal portion of the stent upon fully deploying the proximal portion from the outer constrainment member.

Methods, systems, and devices for providing treatment to a tissue in body lumens are described. The system may include a catheter, an expansion member coupled with a distal portion of the catheter, an ablation structure including one or more longitudinal electrode segments, and an ablation structure support coupled to the ablation structure configured to at least partially unfurl as the expansion member expands and furl as the expansion member contracts. The ablation structure may include multiple separately wired and/or separately controlled longitudinal electrodes, longitudinal electrode zones, or both, such that each longitudinal electrode or longitudinal electrode zone may be selectively enabled or selectively disabled. In some instances, one or more springs are coupled to the ablation structure configured to promote unfurl or furl around the expansion member. In some instances, one or more protection elements are be positioned along the catheter.

Unfurling electrode devices

Methods, apparatuses, and systems are described for minimizing various leakage effects of multi-zone ablation devices. Apparatuses may include an ablation device for treatment of tissue including an ablation structure with a plurality of bipolar electrode zones. Each of the zones may include an in-zone channel pair comprising a positive channel and a negative channel. The ablation structure may be configured such that, for any adjacent electrode zone pair comprising a first electrode zone and a second electrode zone adjacent to the first electrode zone, the positive channel of the first electrode zone is electrically distinct from the positive channel of the second electrode zone, and the negative channel of the first electrode zone is electrically distinct from the negative channel of the second electrode zone. Moreover, the ablation structure may be arranged such that a total number of electrically distinct channels that is less than twice a total number of the plurality of electrode zones.

Arrangement of multi-channel bipolar elecrode zones to minimize leakage and edge effects

Methods, systems, and devices for providing treatment to a target site are described. The system may include a guide assembly, an expandable support device coupled with the distal end of the guide assembly, and an operative member disposed on the expandable support device. The expandable support device may be configured to transition between a collapsed and expanded configuration. The expandable support device may be supported by one or more flexible supports aligned in parallel with an axis about which the expandable support device collapses and/or multiple splines arranged in a pattern configured to promote transitioning of the expandable support device between an expanded and collapsed configuration. The guide assembly may be configured to provide torque to the expandable support device. The operative member can include multiple electrodes arranged in parallel to the axis about which the expandable support device collapses.

Flexible circuit for delivery through a working channel

Arrangement of multi-channel bipolar electrode zones to minimize leakage and edge effects

Methods, apparatuses and systems are described for preventing the over-tightening of a furled ablation structure support around an expandable member. An ablation device for treatment of tissue in body lumens with varying sizes is disclosed. The ablation device may include a catheter, an expansion member coupled with a distal portion of the catheter, and an ablation structure support configured to at least partially unfurl or furl around the expansion member as the expansion member expands or contracts. The ablation device may further include a spacer coupled with the catheter and configured to limit a minimum diameter of the ablation structure support when the expansion member is completely contracted.

Self-sizing catheter features to prevent over-tightening of the electrode

Growing community of inventors

Redwood City, CA, United States of America

Hillary K Huszar