Plantamed Arzneimittel Gmbh

Other

Boehringer Mannheim Gmbh

Klaus Keplinger

Hildebert Wagner

Walter Dorsch

Barbara Kreutzkamp

Sandor Antus

Hermann Stuppner

Certain new phenone derivatives of the formula (I) ##STR1## in which R.sup.1 =CH.sub.3,

Phenone compounds, manufacturing method and pharmaceutical preparations

Method and composition for the treatment of imflammatory conditions

The invention concerns pharmaceutical preparations containing at least one of the following compounds as an active ingredient either alone or in any desired combination: gallic acid, methyl gallate and compounds of the general formula

Pharmaceutical preparations for the treatment of inflammatory diseases

Tetra- and pentacyclic oxindole alkaloids, in particular the alloisopteropodine, isomer A, a pentacyclic oxindole alkaloid, are suitable for the unspecific stimulation of the immunologic system, which has been proved by a substantial percental phagocytosis increase in the granulocytic test according to BRANDT (in vitro), a substantial percental increase of the CL-response in the chemiluminescence test (in vitro) and a high increase of the phagocytosis activity of tissue macrophages of the reticoloendothelial system in the carbon-clearence-test (CCT) according to BIOZZI.

Oxindole alkaloids having properties stimulating the immunologic system

Tetra- and pentacyclic oxindole alkaloids, in particular the alloisopteropodine, isomer A, a pentacyclic oxindole alkaloid, are suitable for the unspecific stimulation of the immunologic system, which has been proved by a substantially percental phagocytosis increase in the granulocytic test according to BRANDT (in vitro), a substantial percental increase of the CL-response in the chemiluminescence test (in vitro) and a high increase of the phagocytosis activity of tissue macrophages of the reticoloendothelial system in the carbon-clearence-test (CCT) according to BIOZZI.

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Breitbrunn am Chiemsee, Germany

Hildebert Wagner