Institut Pasteur

Hilde De Reuse

Val&eacute;rie Cussac

St&eacute;phane Skouloubris

Agn&egrave;s Labigne

Agnes Labigne

Stéphane Skouloubris

Agnés Labigne

Valérie Cussac

Agn&eacute;s Labigne

This application relates to methods of screening molecules capable of inhibiting the survival ofin vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or preventinfection.

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This invention relates to methods of screening molecules capable of inhibiting the survival of in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent infection.

Methods of inhibiting helicobacter pylori

Methods of inhibiting Helicobacter pylori

This invention relates to Helicobacter species aliphatic amidase AmiE polypeptides, the DNA encoding those polypeptides and transformed microorganisms capable of expressing those polypeptides. This invention also relates to the use of Helicobacter sp. (particularly,) amidase AmiE polypeptides and antibodies specific for those polypeptides in immunogenic, therapeutic, and diagnostic applications. The invention additionally relates to processes of producing Helicobacter species aliphatic amidase AmiE polypeptides and intermediates useful in the production of those polypeptides.

Helicobacter aliphatic amidase AmiE polypeptides, and DNA sequences encoding those polypeptides

This invention relates to methods of screening molecules capable of inhibiting the survival of,in vivo by specifically inhibiting the activity of UreI, to the molecules identified by these methods, and to the use of these molecules to treat or prevent,infection.

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Paris, France

Hilde De Reuse