The Salk Institute for Biological Studies

The Public Health Research Institute of the City of New York, Inc.

The Public Health Research Institute

Hilda M Buyoli

Fred Russell Kramer

Paul M Lizardi

Sanjay Tyagi

Cesar E Guerra

Gerald F Joyce

Leslie E Orgel

Barbara C Chu

A probe for the detection of a nucleic acid target sequence containing a molecular switch comprising three essential elements: a probe sequence of 20-60 nucleotides surrounded by switch sequences of 10-40 nucleotides which are complementary to each other, wherein the state of the switch is useful for selectively generating a detectable signal if the probe is hybridized to a target; also, assays and kits utilizing such probes.

Assays and kits incorporating nucleic acid probes containing improved

Nucleic acid process containing improved molecular switch

Growing community of inventors

Mexico City, Mexico

Hilda M Buyoli